CBARP Antibody (A-11): sc-393861

CBARP Antibody (A-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects CBARP protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-CBARP antibody (A-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CBARP, encoded by a gene located on chromosome 19, plays a crucial role in cellular signaling pathways that regulate cell growth and differentiation, making CBARP essential for maintaining normal cellular functions and preventing diseases such as cancer. CBARP′s involvement in these pathways highlights CBARP′s importance in understanding various biological processes and potential therapeutic targets. Chromosome 19 is notable for its high gene density and contains genes linked to significant health conditions, including Peutz-Jeghers syndrome and insulin-dependent diabetes, underscoring the relevance of studying CBARP in the context of human health and disease.

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CBARP Antibody (A-11) References:

1. A fine physical map of the CACNA1A gene region on 19p13.1-p13.2 chromosome.  |  Trettel, F., et al. 2000. Gene. 241: 45-50. PMID: 10607897
2. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).  |  LaPoint, SF., et al. 2000. Adv Anat Pathol. 7: 307-21. PMID: 10976909
3. Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters.  |  Moodie, SJ., et al. 2002. Eur J Immunogenet. 29: 287-91. PMID: 12121272
4. Search for the second Peutz-Jeghers syndrome locus: exclusion of the STK13, PRKCG, KLK10, and PSCD2 genes on chromosome 19 and the STK11IP gene on chromosome 2.  |  Buchet-Poyau, K., et al. 2002. Cytogenet Genome Res. 97: 171-8. PMID: 12438709
5. The DNA sequence and biology of human chromosome 19.  |  Grimwood, J., et al. 2004. Nature. 428: 529-35. PMID: 15057824
6. Immunogenetics of killer cell immunoglobulin-like receptors.  |  Parham, P. 2005. Mol Immunol. 42: 459-62. PMID: 15607799
7. BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription.  |  Brocke-Heidrich, K., et al. 2006. Oncogene. 25: 7297-304. PMID: 16732314
8. A novel CADASIL-causing mutation in a stroke patient.  |  Vikelis, M., et al. 2007. Swiss Med Wkly. 137: 323-5. PMID: 17629811
9. BARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosis.  |  Béguin, P., et al. 2014. J Cell Biol. 205: 233-49. PMID: 24751537
10. Black Raspberry Inhibits Oral Tumors in Mice Treated with the Tobacco Smoke Constituent Dibenzo(def,p)chrysene Via Genetic and Epigenetic Alterations.  |  Chen, KM., et al. 2020. Cancer Prev Res (Phila). 13: 357-366. PMID: 31969344
11. Chromosomal localization of the carcinoembryonic antigen gene family and differential expression in various tumors.  |  Zimmermann, W., et al. 1988. Cancer Res. 48: 2550-4. PMID: 3356015
12. The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite development within the tsetse vector.  |  Casas-Sanchez, A., et al. 2023. PLoS Pathog. 19: e1011269. PMID: 36996244

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CBARP Antibody (A-11) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-CBARP Antibody (A-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CBARP Antibody (A-11) Specifications

Alternate Product Name: CBARP

Product Clone Name: A-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 324-353

Epitope Target: CBARP

Epitope Species: human

Product Reactivity/Detection: CBARP

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for CBARP Antibody (A-11): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin