cathepsin V Antibody (CV55-3G11): sc-32798
- cathepsin V Antibody (CV55-3G11) is a mouse monoclonal IgG1 κ cathepsin V antibody, cited in 1 publications, provided at 200 µg/ml
- raised against human cathepsin V-specific peptides
- cathepsin V Antibody (CV55-3G11) is recommended for detection of cathepsin V of human origin by WB, IP and IF
- Anti-cathepsin V Antibody (CV55-3G11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for cathepsin V Antibody (CV55-3G11) for WB applications. These reagents are now offered in bundles with cathepsin V Antibody (CV55-3G11) (see ordering information below).
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SEE ALSO...
Cathepsin V Antibody (CV55-3G11) is a mouse monoclonal IgG1 kappa light chain antibody that detects human cathepsin V protein through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-cathepsin V antibody (CV55-3G11) is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cathepsin V, also known as CTSU, CTSV, CATL2, or cathepsin U, is a lysosomal cysteine proteinase that plays a crucial role in corneal physiology and participates in invariant chain degradation within human thymus. Cathepsin V protein is primarily found in corneal epithelium, activated macrophages, and appears in colorectal and breast carcinomas, highlighting significance in both normal and pathological processes. A 1.8-kb mRNA transcript for cathepsin V exists in normal human thymus and testis, underscoring importance in immune function and development. As a peptidase C1 family member, cathepsin V synthesizes as a preproenzyme, processing into proenzymes that either target lysosomes or follow cellular secretory pathways, supporting various cellular functions and interactions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
cathepsin V Antibody (CV55-3G11) References:
- Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization. | Brömme, D., et al. 1999. Biochemistry. 38: 2377-85. PMID: 10029531
- Genomic organization and chromosomal localization of the human cathepsin L2 gene. | Itoh, R., et al. 1999. DNA Res. 6: 137-40. PMID: 10382972
- Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis. | Tolosa, E., et al. 2003. J Clin Invest. 112: 517-26. PMID: 12925692
- Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages. | Yasuda, Y., et al. 2004. J Biol Chem. 279: 36761-70. PMID: 15192101
- Cathepsin L2, a novel human cysteine proteinase produced by breast and colorectal carcinomas. | Santamaría, I., et al. 1998. Cancer Res. 58: 1624-30. PMID: 9563472
- Isolation and characterization of human cathepsin V: a major proteinase in corneal epithelium. | Adachi, W., et al. 1998. Invest Ophthalmol Vis Sci. 39: 1789-96. PMID: 9727401
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cathepsin V Antibody (CV55-3G11) | sc-32798 | 200 µg/ml | $316.00 | |||
cathepsin V Antibody (CV55-3G11): m-IgG Fc BP-HRP Bundle | sc-526691 | 200 µg Ab; 10 µg BP | $354.00 | |||
cathepsin V Antibody (CV55-3G11): m-IgG1 BP-HRP Bundle | sc-532064 | 200 µg Ab; 20 µg BP | $354.00 | |||
cathepsin V Antibody (CV55-3G11) AC | sc-32798 AC | 500 µg/ml, 25% agarose | $416.00 | |||
cathepsin V Antibody (CV55-3G11) HRP | sc-32798 HRP | 200 µg/ml | $316.00 | |||
cathepsin V Antibody (CV55-3G11) FITC | sc-32798 FITC | 200 µg/ml | $330.00 | |||
cathepsin V Antibody (CV55-3G11) PE | sc-32798 PE | 200 µg/ml | $343.00 | |||
cathepsin V Antibody (CV55-3G11) Alexa Fluor® 488 | sc-32798 AF488 | 200 µg/ml | $357.00 | |||
cathepsin V Antibody (CV55-3G11) Alexa Fluor® 546 | sc-32798 AF546 | 200 µg/ml | $357.00 | |||
cathepsin V Antibody (CV55-3G11) Alexa Fluor® 594 | sc-32798 AF594 | 200 µg/ml | $357.00 | |||
cathepsin V Antibody (CV55-3G11) Alexa Fluor® 647 | sc-32798 AF647 | 200 µg/ml | $357.00 | |||
cathepsin V Antibody (CV55-3G11) Alexa Fluor® 680 | sc-32798 AF680 | 200 µg/ml | $357.00 | |||
cathepsin V Antibody (CV55-3G11) Alexa Fluor® 790 | sc-32798 AF790 | 200 µg/ml | $357.00 |