Date published: 2025-11-20

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cathepsin S Antibody (G-5): sc-74429

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Datasheets
  • cathepsin S Antibody (G-5) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
  • raised against amino acids 191-240 cathepsin S of human origin
  • recommended for detection of cathepsin S of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • See cathepsin S (E-3): sc-271619 for cathepsin S antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for cathepsin S Antibody (G-5) for WB and IHC(P) applications. These reagents are now offered in bundles with cathepsin S Antibody (G-5) (see ordering information below).

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cathepsin S Antibody (G-5) is a mouse monoclonal IgG1 antibody that detects cathepsin S in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Cathepsin S is a crucial cysteine protease that plays a significant role in the immune response by facilitating the processing of antigens and the degradation of extracellular matrix components, which is vital for tissue remodeling and repair. This enzyme is predominantly located in lysosomes, where cathepsin S contributes to the degradation of proteins and peptides, thus maintaining cellular homeostasis. Proper functioning of cathepsin S is essential, as dysregulation can lead to various pathological conditions, including autoimmune diseases and cancer. Additionally, cathepsin S interacts with specific proteins such as cathepsin L and cystatin C, which are involved in the regulation of proteolytic activity, further underscoring cathepsin S importance in cellular processes. With versatile applications and critical role in cellular metabolism, anti-cathepsin S antibody (G-5) serves as an invaluable tool for researchers studying proteolytic enzymes and their implications in health and disease.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

cathepsin S Antibody (G-5)

sc-74429
200 µg/ml
$316.00

cathepsin S Antibody (G-5): m-IgG Fc BP-HRP Bundle

sc-539518
200 µg Ab; 10 µg BP
$354.00

cathepsin S Antibody (G-5): m-IgG1 BP-HRP Bundle

sc-541539
200 µg Ab; 20 µg BP
$354.00

I am using cathepsin S (G-5): sc-74429 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Randy McDonald
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Worked well with a little background for WB in GAWorked well with a little background for WB in GA-10 (A) and U-87 MG (B) whole cell lysates. -SCBT QC
Date published: 2015-04-15
Rated 5 out of 5 by from Produced beautiful immunoperoxidase cytoplasmicProduced beautiful immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human gall bladder tissue. -SCBT QC
Date published: 2015-01-18
Rated 5 out of 5 by from Single strong band for WB in human cathepsinSingle strong band for WB in human cathepsin S transfected(B) 293T whole cell lysates. -SCBT QC
Date published: 2015-01-07
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cathepsin S Antibody (G-5) is rated 5.0 out of 5 by 3.
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