catalase Antibody (E-7): sc-365738

Catalase Antibody (E-7) is a mouse monoclonal IgG1 light chain antibody that detects catalase in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Catalase is a crucial enzyme located primarily in peroxisomes, where catalase plays a vital role in the detoxification of hydrogen peroxide, a harmful byproduct of cellular metabolism. By converting hydrogen peroxide into water and oxygen, catalase protects cells from oxidative damage and maintains cellular homeostasis, which is particularly important in tissues with high metabolic activity. Deficiencies in catalase can lead to severe oxidative stress, contributing to various diseases, including acatalasia, characterized by the absence of catalase activity and associated with ulcerating oral lesions. Furthermore, catalase′s ability to form a homotetramer enhances catalase stability and efficiency in detoxifying reactive oxygen species, making catalase an essential protein for cellular health and a significant focus of research in understanding oxidative stress-related conditions.

The preferred catalase antibody is catalase Antibody (H-9): sc-271803.