catalase Antibody (A-4): sc-271358

Catalase Antibody (A-4) is a mouse monoclonal IgG3 antibody that detects catalase in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Catalase is a crucial enzyme located primarily in peroxisomes, where catalase plays a vital role in the detoxification of hydrogen peroxide, a harmful byproduct of cellular metabolism. By converting hydrogen peroxide into water and oxygen, catalase protects cells from oxidative damage, which is essential for maintaining cellular health and preventing inflammation. Deficiencies in catalase can lead to conditions such as acatalasia, characterized by the absence of catalase activity in red blood cells, resulting in ulcerating oral lesions and increased susceptibility to oxidative stress. The ability of catalase to form a homotetramer enhances catalase stability and efficiency in catalyzing the breakdown of hydrogen peroxide, making catalase a key player in cellular defense mechanisms. Anti-catalase antibody (A-4) is an invaluable tool for researchers studying oxidative stress, inflammation, and related diseases, providing insights into the protective roles of this important enzyme.

The preferred catalase antibody is catalase Antibody (H-9): sc-271803.