CANT1 Antibody (14.9): sc-100662

CANT1 Antibody (14.9) is a mouse monoclonal IgG2a antibody that detects CANT1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). CANT1, also known as calcium-activated nucleotidase 1, is a 401 amino acid single-pass type II membrane protein predominantly located in the endoplasmic reticulum and Golgi apparatus, where CANT1 plays a crucial role in nucleotide metabolism. CANT1 is a member of the apyrase family and functions as a calcium-dependent nucleotidase that preferentially hydrolyzes UDP, which is vital for various cellular processes, including energy metabolism and signaling pathways. CANT1 is expressed at its highest levels in tissues such as the testis, placenta, prostate, and small intestine, and CANT1 undergoes post-translational N-glycosylation and alternative splicing, resulting in the production of two distinct isoforms. Notably, mutations in the CANT1 gene are linked to Desbuquois dysplasia, a rare autosomal recessive chondrodysplasia characterized by significant prenatal and postnatal growth retardation, underscoring CANT1′s importance in normal development and cellular function. Anti-CANT1 antibody (14.9) is an essential tool for researchers studying CANT1′s role in health and disease.

The preferred CANT1 antibody is CANT1 Antibody (C-3): sc-515574.