CaMKIIα Antibody (45) is a mouse monoclonal IgG1 antibody that detects CaMKIIα in mouse, rat, human, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). CaMKIIα, a member of the calcium/calmodulin-dependent protein kinase family, plays a crucial role in various cellular processes, including the regulation of synaptic plasticity and memory formation in neurons. CaMKIIα is primarily located in the cytoplasm and translocates to the nucleus upon activation, which is essential for modulating gene expression and cellular signaling pathways. CaMKIIα′s interaction with other proteins, such as the NMDA receptor and various transcription factors, underscores its importance in mediating calcium signaling and its implications in neurodegenerative diseases and cognitive disorders. CaMKIIα undergoes post-translational modifications, including phosphorylation, which can influence activity and interactions, further highlighting significance in cellular signaling networks. With broad species reactivity and proven applications, anti-CaMKIIα antibody (45) serves as an invaluable tool for researchers studying calcium signaling and its effects on cellular functions.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CAMK2A/CaMKII alpha Antibody (45) | sc-136212 | 50 µg/0.5 ml | $316.00 |