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CAMK2A/CaMKII alpha Antibody (45): sc-136212

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Datasheets
  • CAMK2A/CaMKII alpha Antibody (45) is a mouse monoclonal IgG1, cited in 1 publications, provided at 50 µg/0.5 ml
  • raised against amino acids 448-460 of CaMKIIα of rat origin
  • recommended for detection of CaMKIIα of mouse, rat, human and canine origin by WB, IP and IF
  • See CaMKII (G-1): sc-5306 for CAMK2A/CaMKII alpha antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CAMK2A/CaMKII alpha Antibody (45). This work is in progress.

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CaMKIIα Antibody (45) is a mouse monoclonal IgG1 antibody that detects CaMKIIα in mouse, rat, human, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). CaMKIIα, a member of the calcium/calmodulin-dependent protein kinase family, plays a crucial role in various cellular processes, including the regulation of synaptic plasticity and memory formation in neurons. CaMKIIα is primarily located in the cytoplasm and translocates to the nucleus upon activation, which is essential for modulating gene expression and cellular signaling pathways. CaMKIIα′s interaction with other proteins, such as the NMDA receptor and various transcription factors, underscores its importance in mediating calcium signaling and its implications in neurodegenerative diseases and cognitive disorders. CaMKIIα undergoes post-translational modifications, including phosphorylation, which can influence activity and interactions, further highlighting significance in cellular signaling networks. With broad species reactivity and proven applications, anti-CaMKIIα antibody (45) serves as an invaluable tool for researchers studying calcium signaling and its effects on cellular functions.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

CAMK2A/CaMKII alpha Antibody (45)

sc-136212
50 µg/0.5 ml
$316.00

Does Santacruz sell the immunogen peptide, 448-460 for the CaMKII antibody (45)?

Asked by: takeo3v
Thank you for your question. No, we do not sell the antigen used to generate this antibody.
Answered by: Technical Support
Date published: 2019-05-04

I am using CaMKIIα (45): sc-136212 for immunofluorescence, what dilution of this antibody should I use?

Asked by: cjMara
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-03-24
  • y_2025, m_9, d_27, h_6CST
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Rated 4 out of 5 by from Good band for WB in IMRGood band for WB in IMR-32 and U-87 MG whole cell lysates. -SCBT QC
Date published: 2013-03-27
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CAMK2A/CaMKII alpha Antibody (45) is rated 4.0 out of 5 by 1.
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