Calretinin Antibody (D-12): sc-365989
- Calretinin Antibody (D-12) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-27 at the N-terminus of Calretinin of human origin
- recommended for detection of Calretinin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and porcine
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Calretinin Antibody (D-12) for WB applications. These reagents are now offered in bundles with Calretinin Antibody (D-12) (see ordering information below).
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Calretinin Antibody (D-12) is a mouse monoclonal IgG1 antibody that detects Calretinin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Calretinin is a vital intracellular calcium-binding protein that plays a crucial role in calcium signaling, which is essential for various cellular processes, including neurotransmitter release and muscle contraction. Anti-Calretinin antibody (D-12) helps maintain cellular homeostasis and modulates the activity of calcium-dependent enzymes, making Calretinin particularly important in neurons where precise calcium regulation is necessary for synaptic transmission and plasticity. Calretinin is predominantly located in the brain, especially in auditory neurons, where Calretinin contributes to the precise timing of neuronal discharges, thereby influencing auditory processing. Calretinin (D-12) antibody is widely utilized as an immunocytochemical marker for mesothelioma, highlighting Calretinin′s significance in both research and clinical diagnostics.
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Calretinin Antibody (D-12) References:
- Immunoreactivity pattern of calretinin in the developing human cerebellar cortex. | Pibiri, V., et al. 2017. Acta Histochem. 119: 228-234. PMID: 28174028
- Posttranscriptional Regulation Controls Calretinin Expression in Malignant Pleural Mesothelioma. | Kresoja-Rakic, J., et al. 2017. Front Genet. 8: 70. PMID: 28611824
- Selective Loss of Calretinin-Poor Cochlear Afferent Nerve Fibers in Streptozotocin-Induced Hyperglycemic Mice. | Kang, KW., et al. 2020. J Nanosci Nanotechnol. 20: 5515-5519. PMID: 32331128
- Expression of calbindin and calretinin in the dorsomedial and ventromedial hypothalamic nuclei during aging. | Vishnyakova, PA., et al. 2021. Anat Rec (Hoboken). 304: 1094-1104. PMID: 33040447
- Expression of Calretinin, Marker of Mesothelial Differentiation, in Pancreatic Ductal Adenocarcinoma: A Potential Diagnostic Pitfall. | Askan, G. and Basturk, O. 2021. Turk Patoloji Derg. 37: 115-120. PMID: 33432559
- Diagnostic Role of Calretinin in Suspicious Cases of Hirschsprung's Disease. | Singh, SK., et al. 2021. Cureus. 13: e13373. PMID: 33754098
- Comparison of calretinin expression in dentigerous cysts and ameloblastoma: An immunohistochemical study. | Varshney, A., et al. 2020. Natl J Maxillofac Surg. 11: 224-230. PMID: 33897185
- Characterization of the Transition Zone in Short Segment Hirschsprung Disease Using Calretinin Immunostaining. | Righini-Grunder, F., et al. 2022. Pediatr Dev Pathol. 25: 270-277. PMID: 34875924
- Calretinin-immunoreactive neurons in the human striatum. | Parent, A., et al. 1995. Brain Res. 674: 347-51. PMID: 7796115
- Characterization of calretinin-immunoreactive structures in the striatum of the rat. | Bennett, BD. and Bolam, JP. 1993. Brain Res. 609: 137-48. PMID: 8508297
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Calretinin Antibody (D-12) | sc-365989 | 200 µg/ml | $316.00 | |||
Calretinin Antibody (D-12): m-IgG Fc BP-HRP Bundle | sc-537861 | 200 µg Ab; 10 µg BP | $354.00 | |||
Calretinin Antibody (D-12): m-IgGκ BP-HRP Bundle | sc-535293 | 200 µg Ab; 40 µg BP | $354.00 | |||
Calretinin Antibody (D-12): m-IgG1 BP-HRP Bundle | sc-545411 | 200 µg Ab; 20 µg BP | $354.00 | |||
Calretinin (D-12) Neutralizing Peptide | sc-365989 P | 100 µg/0.5 ml | $68.00 |