Calgranulin A/B Antibody (5.5): sc-53186

Calgranulin A/B Antibody (5.5) is a mouse monoclonal IgG1 kappa light chain antibody that detects the Calgranulin A/B protein of human origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Calgranulin A/B, also known as MRP8 and MRP14, is part of the S100 protein family, which is characterized by its EF-hand calcium-binding motifs. Calgranulin A/B plays a crucial role in the inflammatory response and is primarily expressed in myeloid cells, such as macrophages and neutrophils, where Calgranulin A/B is involved in the regulation of various cellular processes, including cell proliferation, differentiation, and apoptosis. Calgranulin A/B′s presence in immune cells highlights its importance in modulating immune responses and potential as a biomarker for inflammatory diseases. Additionally, Calgranulin A/B can interact with other proteins, such as S100A8, to form heterodimers that enhance functional capabilities, further underscoring Calgranulin A/B′s significance in cellular signaling pathways. Calgranulin A/B′s ability to bind calcium ions also suggests a role in calcium homeostasis within cells, which is vital for maintaining cellular functions and signaling. With diverse roles in immune regulation and cellular processes, Calgranulin A/B is a valuable target for research in inflammation and immune-related conditions.

The preferred Calgranulin A antibody is Calgranulin A Antibody (C-10): sc-48352.