Caldesmon Antibody (8): sc-135965
- Caldesmon Antibody (8) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
- raised against amino acids 251-395 of L-Caldesmon of human origin
- recommended for detection of H-Caldesmon and L-Caldesmon of mouse, rat and human origin by WB, IP and IF; not recommended for IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Caldesmon Antibody (8). This work is in progress.
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Caldesmon Antibody (8) is a mouse monoclonal IgG1 antibody that detects Caldesmon in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Caldesmon is a crucial actin-binding protein that plays a significant role in muscle contraction and cellular motility, making Caldesmon essential for various physiological processes. Caldesmon exists in two main forms: muscular Caldesmon, predominantly found in smooth muscle, and non-muscular Caldesmon, which is expressed in a variety of non-muscle tissues. Muscular Caldesmon, also known as high molecular weight Caldesmon or H-Caldesmon, interacts with actin filaments and is involved in the regulation of smooth muscle contraction, while non-muscular Caldesmon, referred to as low molecular weight Caldesmon or L-Caldesmon, is implicated in cellular signaling and structural integrity in non-muscle cells. Multiple isoforms, resulting from alternative splicing of the Caldesmon gene, allow for diverse functional roles in different tissue types. Anti-Caldesmon antibody (8) serves as an invaluable tool for researchers studying the dynamics of actin filament interactions and the regulatory mechanisms underlying muscle and non-muscle cell functions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Caldesmon Antibody (8) | sc-135965 | 50 µg/0.5 ml | $322.00 |