CALCOCO2 Antibody (E-10): sc-393042

CALCOCO2 Antibody (E-10) is a mouse monoclonal IgG1 antibody that detects CALCOCO2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CALCOCO2, also known as nuclear dot protein 52 (NDP52), is a 446 amino acid protein that plays a crucial role in cellular processes by localizing to the perinuclear region of the cytoplasm and nuclear dots, where CALCOCO2 acts as a subunit of nuclear domain 10 (ND10) bodies. These ND10 bodies are believed to be associated with the nuclear matrix and are implicated in the life cycles of various viruses, including herpes simplex virus type 1 (HSV-1). CALCOCO2′s importance extends beyond structural roles; CALCOCO2 is involved in the organization of the actin cytoskeleton and ruffle formation, which are essential for cell motility and shape. Additionally, CALCOCO2 interacts with proteins such as Myosin VI, highlighting CALCOCO2′s significance in membrane trafficking pathways, cell adhesion, and cytokine signaling. The regulation of these processes by CALCOCO2 underscores CALCOCO2′s vital contribution to developmental events and cellular homeostasis, making CALCOCO2 a key target for research in cell biology and virology.

The preferred CALCOCO2 antibody is CALCOCO2 Antibody (F-6): sc-376540.