Calcidiol Antibody (ID1-25B): sc-73499

Calcidiol Antibody (ID1-25B) is a mouse monoclonal IgG1 antibody that detects Calcidiol, also known as 25-hydroxyvitamin D3 or 25-OH D3, in non-species reactive samples by enzyme-linked immunosorbent assay (ELISA). Anti-Calcidiol antibody (ID1-25B) is available in a non-conjugated form, providing researchers with a versatile tool for studying vitamin D metabolism. Calcidiol serves as a crucial prehormone in the body, being the primary circulating form of vitamin D and a precursor to its active metabolite, calcitriol. The conversion of calcidiol to calcitriol occurs primarily in the kidneys, where the enzyme 1α-hydroxylase catalyzes this transformation. This process is vital for maintaining calcium and phosphate homeostasis, as calcitriol enhances the absorption of these minerals in the intestines, promotes their reabsorption in the kidneys, and facilitates bone resorption. Furthermore, calcitriol′s role extends beyond mineral metabolism; calcitriol is also involved in regulating immune responses and cellular differentiation, making calcitriol essential for overall health. Calcidiol monoclonal antibody (ID1-25B) enables researchers to gain insights into the physiological roles of vitamin D and its impact on various biological processes.

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Calcidiol Antibody (ID1-25B) References:

1. A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial.  |  Lips, P., et al. 2001. J Clin Endocrinol Metab. 86: 1212-21. PMID: 11238511
2. Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes.  |  Stoffels, K., et al. 2006. J Bone Miner Res. 21: 37-47. PMID: 16355272
3. Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway.  |  Wjst, M., et al. 2006. Respir Res. 7: 60. PMID: 16600026
4. 25(OH) vitamin D3 in patients with chronic kidney disease and those on dialysis: rediscovering its importance.  |  Taskapan, H., et al. 2006. Int Urol Nephrol. 38: 323-9. PMID: 16868705
5. Measurement of vitamin D status: background, clinical use, and methodologies.  |  Hart, GR., et al. 2006. Clin Lab. 52: 335-43. PMID: 16955631
6. Decreased in vitro osteoblast proliferation and low turnover bone disease in nonuremic proteinuric patients.  |  Dias, CB., et al. 2007. Kidney Int. 71: 562-8. PMID: 17228363
7. Production of 10-oxo-19-nor-25-hydroxyvitamin D3 by solubilized kidney mitochondria from chick and rat.  |  Brown, AJ. and DeLuca, HF. 1985. J Biol Chem. 260: 14132-6. PMID: 2997195
8. Differentiation of a human monocytic cell line by 1,25-dihydroxyvitamin D3 (calcitriol): a morphologic, phenotypic, and functional analysis.  |  Rigby, WF., et al. 1984. Blood. 64: 1110-5. PMID: 6548394
9. The nuclear vitamin D receptor: biological and molecular regulatory properties revealed.  |  Haussler, MR., et al. 1998. J Bone Miner Res. 13: 325-49. PMID: 9525333

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Calcidiol Antibody (ID1-25B) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Calcidiol Antibody (ID1-25B) Specifications

Alternate Product Name: Calcidiol

Product Clone Name: ID1-25B

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Calcidiol

Epitope Species:

Product Reactivity/Detection: Calcidiol, also designated 25-hydroxyvitamin-D₃ or 25-OH D₃,

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide, 0.1% gelatin and < 0.1% stabilizer protein

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Calcidiol Antibody (ID1-25B): N/A