CAF-1 p60 Antibody (B-10): sc-393662
- CAF-1 p60 Antibody (B-10) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-80 mapping at the N-terminus of CAF-1 p60 of human origin
- Anti-CAF-1 p60 Antibody (B-10) is recommended for detection of CAF-1 p60 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CAF-1 p60 Antibody (B-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CAF-1 p60 Antibody (B-10). This work is in progress.
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CAF-1 p60 Antibody (B-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects CAF-1 p60 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-CAF-1 p60 antibody (B-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The chromatin assembly factor-1 (CAF-1) complex, which includes the p60 subunit, plays a crucial role in the assembly of nucleosomes by depositing newly synthesized and acetylated histones H3 and H4 into nascent chromatin during DNA replication. This process is vital for maintaining genomic integrity and regulating gene expression, as proper nucleosome assembly is essential for the accessibility of DNA to transcription factors and other regulatory proteins. Additionally, the p60 subunit is involved in dynamic interactions with heterochromatin, which is characterized by a tightly packed structure that generally replicates later in the S phase of the cell cycle. The ability of CAF-1 to facilitate the orderly assembly of histones and heterochromatin proteins during DNA replication underscores its importance in epigenetic regulation and cellular function.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CAF-1 p60 Antibody (B-10) | sc-393662 | 200 µg/ml | $316.00 | |||
CAF-1 p60 Antibody (B-10) AC | sc-393662 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CAF-1 p60 Antibody (B-10) HRP | sc-393662 HRP | 200 µg/ml | $316.00 | |||
CAF-1 p60 Antibody (B-10) FITC | sc-393662 FITC | 200 µg/ml | $330.00 | |||
CAF-1 p60 Antibody (B-10) PE | sc-393662 PE | 200 µg/ml | $343.00 | |||
CAF-1 p60 Antibody (B-10) Alexa Fluor® 488 | sc-393662 AF488 | 200 µg/ml | $357.00 | |||
CAF-1 p60 Antibody (B-10) Alexa Fluor® 546 | sc-393662 AF546 | 200 µg/ml | $357.00 | |||
CAF-1 p60 Antibody (B-10) Alexa Fluor® 594 | sc-393662 AF594 | 200 µg/ml | $357.00 | |||
CAF-1 p60 Antibody (B-10) Alexa Fluor® 647 | sc-393662 AF647 | 200 µg/ml | $357.00 | |||
CAF-1 p60 Antibody (B-10) Alexa Fluor® 680 | sc-393662 AF680 | 200 µg/ml | $357.00 | |||
CAF-1 p60 Antibody (B-10) Alexa Fluor® 790 | sc-393662 AF790 | 200 µg/ml | $357.00 |