cadherin-16 Antibody (E-7): sc-393153

Cadherin-16 Antibody (E-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects cadherin-16 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-cadherin-16 antibody (E-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cadherin-16, also known as Ksp-cadherin, is a type I membrane protein that plays a crucial role in kidney function by mediating cell-cell adhesion specifically in renal tubular epithelial cells. Cadherin-16 is localized exclusively to the basolateral membrane of these cells, which is essential for maintaining the integrity of the renal epithelium and facilitating proper kidney filtration and reabsorption processes. The human Ksp-cadherin gene is located on chromosome 16q22, while the mouse counterpart is found in a highly syntenic region of distal chromosome 8. The unique structure of cadherin-16, characterized by a large extracellular domain containing five homologous repeats, is vital for binding specificity and function in cellular adhesion, making cadherin-16 an important target for studies related to kidney health and disease.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-cadherin-16 Antibody (E-7) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-cadherin-16 Antibody (E-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

cadherin-16 Antibody (E-7) Specifications

Alternate Product Name: CDH16

Product Clone Name: E-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-300

Epitope Target: cadherin-16

Epitope Species: mouse

Product Reactivity/Detection: cadherin-16

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for cadherin-16 Antibody (E-7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred cadherin-16 antibody is cadherin-16 Antibody (H-10): sc-393132.