C3 Antibody (C-4): sc-25298
- C3 Antibody (C-4) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 541-840 of C3 of human origin
- recommended for detection of C3 precursor, C3a anaphylatoxin, C3 α chain, C3 β chain and C3b α′ chain of human origin by WB, IP, IF and ELISA
- See C3 (B-9): sc-28294 for C3 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for C3 Antibody (C-4) for WB applications. These reagents are now offered in bundles with C3 Antibody (C-4) (see ordering information below).
C3 Antibody (C-4) is a mouse monoclonal IgG2a kappa light chain antibody raised against amino acids 541-840 of the human Complement Component 3 (C3) protein. C3, also known as CPAMD1 or acylation-stimulating protein (ASP), is a central component of the complement system, playing a crucial role in innate immunity by mediating opsonization, inflammation, and cell lysis. Upon activation, C3 is cleaved into C3a and C3b fragments; C3a acts as a potent anaphylatoxin inducing inflammatory responses, while C3b binds to pathogen surfaces, promoting their clearance by phagocytes. Dysregulation of C3 activation is associated with various pathological conditions, including autoimmune diseases and increased susceptibility to infections. anti-C3 antibody (C-4) specifically recognizes the C3 precursor, C3a anaphylatoxin, C3 α chain, C3 β chain, and C3b α′ chain of human origin, and is recommended for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA) assays. By targeting a key region of C3, C3 (C-4) antibody serves as a valuable tool for studying complement activation pathways and their implications in immune response. anti-C3 antibody (C-4) makes an essential contribution to research in immunology and related biomedical fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
C3 Antibody (C-4) | sc-25298 | 200 µg/ml | $322.00 | |||
C3 Antibody (C-4): m-IgG Fc BP-HRP Bundle | sc-536704 | 200 µg Ab; 10 µg BP | $361.00 | |||
C3 Antibody (C-4): m-IgGκ BP-HRP Bundle | sc-533864 | 200 µg Ab; 40 µg BP | $361.00 | |||
C3 Antibody (C-4): m-IgG2a BP-HRP Bundle | sc-547852 | 200 µg Ab; 10 µg BP | $361.00 |