C12orf4 Antibody (E-12): sc-514328
- C12orf4 Antibody (E-12) is a mouse monoclonal IgG1 κ C12orf4 antibody provided at 200 µg/ml
- raised against amino acids 87-256 mapping within an internal region of C12orf4 of human origin
- C12orf4 Antibody (E-12) is recommended for detection of C12orf4 of human and mouse origin, and LOC297607 of rat origin by WB, IP, IF and ELISA
- Anti-C12orf4 Antibody (E-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for C12orf4 Antibody (E-12) for WB applications. These reagents are now offered in bundles with C12orf4 Antibody (E-12) (see ordering information below).
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C12orf4 Antibody (E-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects C12orf4 protein of human and mouse origin, as well as LOC297607 protein of rat origin, by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-C12orf4 antibody (E-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. C12orf4 plays a significant role in cellular processes, particularly in the regulation of gene expression and cellular signaling pathways, which are crucial for maintaining normal cellular function and development. Dysregulation of C12orf4 has been implicated in various skeletal deformities and developmental disorders, highlighting C12orf4′s importance in morphogenesis and cellular homeostasis. Additionally, chromosome 12, where C12orf4 gene is located, harbors a homeobox gene cluster that encodes essential transcription factors, further emphasizing C12orf4′s role in developmental biology. Understanding C12orf4 function is vital for elucidating molecular mechanisms underlying these disorders and could provide insights into potential therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
C12orf4 Antibody (E-12) References:
- The genomic context of natural killer receptor extended gene families. | Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
- Genotype/phenotype analysis in a patient with pure and complete trisomy 12p. | Zumkeller, W., et al. 2004. Am J Med Genet A. 129A: 261-4. PMID: 15326625
- The phenotypic spectrum of COL2A1 mutations. | Nishimura, G., et al. 2005. Hum Mutat. 26: 36-43. PMID: 15895462
- Comparative genomics of natural killer cell receptor gene clusters. | Kelley, J., et al. 2005. PLoS Genet. 1: 129-39. PMID: 16132082
- The natural history of trisomy 12p. | Segel, R., et al. 2006. Am J Med Genet A. 140: 695-703. PMID: 16502429
- Noonan syndrome. | van der Burgt, I. 2007. Orphanet J Rare Dis. 2: 4. PMID: 17222357
- Cytogenetic and molecular analysis in trisomy 12p. | Allen, TL., et al. 1996. Am J Med Genet. 63: 250-6. PMID: 8723118
- Low basal transcripts of the COL2A1 collagen gene from lymphoblasts show alternative splicing of exon 12 in the Kniest form of spondyloepiphyseal dysplasia. | Yang, W. and Cole, WG. 1998. Hum Mutat. Suppl 1: S1-2. PMID: 9452022
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
C12orf4 Antibody (E-12) | sc-514328 | 200 µg/ml | $316.00 | |||
C12orf4 Antibody (E-12): m-IgG Fc BP-HRP Bundle | sc-531093 | 200 µg Ab; 10 µg BP | $354.00 | |||
C12orf4 Antibody (E-12): m-IgGκ BP-HRP Bundle | sc-524688 | 200 µg Ab, 40 µg BP | $354.00 | |||
C12orf4 Antibody (E-12): m-IgG1 BP-HRP Bundle | sc-544394 | 200 µg Ab; 20 µg BP | $354.00 | |||
C12orf4 Antibody (E-12) AC | sc-514328 AC | 500 µg/ml, 25% agarose | $416.00 | |||
C12orf4 Antibody (E-12) HRP | sc-514328 HRP | 200 µg/ml | $316.00 | |||
C12orf4 Antibody (E-12) FITC | sc-514328 FITC | 200 µg/ml | $330.00 | |||
C12orf4 Antibody (E-12) PE | sc-514328 PE | 200 µg/ml | $343.00 | |||
C12orf4 Antibody (E-12) Alexa Fluor® 488 | sc-514328 AF488 | 200 µg/ml | $357.00 | |||
C12orf4 Antibody (E-12) Alexa Fluor® 546 | sc-514328 AF546 | 200 µg/ml | $357.00 | |||
C12orf4 Antibody (E-12) Alexa Fluor® 594 | sc-514328 AF594 | 200 µg/ml | $357.00 | |||
C12orf4 Antibody (E-12) Alexa Fluor® 647 | sc-514328 AF647 | 200 µg/ml | $357.00 | |||
C12orf4 Antibody (E-12) Alexa Fluor® 680 | sc-514328 AF680 | 200 µg/ml | $357.00 | |||
C12orf4 Antibody (E-12) Alexa Fluor® 790 | sc-514328 AF790 | 200 µg/ml | $357.00 |