C11orf24 Antibody (E-11): sc-514397

C11orf24 Antibody (E-11) is a mouse monoclonal IgM antibody that detects C11orf24 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-C11orf24 antibody (E-11) is available as a non-conjugated format. C11orf24, also known as DM4E3, is a 449 amino acid single-pass type I membrane protein that plays a crucial role in cellular signaling and communication, particularly in the nervous system. C11orf24 expression is notably high in the heart, placenta, liver, pancreas, and colon, while also being found in various other tissues including the brain, lung, skeletal muscle, kidney, spleen, prostate, testis, ovary, and small intestine. C11orf24 localization in these tissues suggests involvement in diverse physiological processes, including development and immune responses. The gene encoding C11orf24 is located on human chromosome 11, a region known for dense gene and disease associations, which underscores potential implications in various pathologies. Understanding C11orf24 function and distribution can provide insights into health and disease, making C11orf24 (E-11) monoclonal antibody a valuable research tool.

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C11orf24 Antibody (E-11) References:

1. The 11q terminal deletion disorder: a prospective study of 110 cases.  |  Grossfeld, PD., et al. 2004. Am J Med Genet A. 129A: 51-61. PMID: 15266616
2. Human chromosome 11 DNA sequence and analysis including novel gene identification.  |  Taylor, TD., et al. 2006. Nature. 440: 497-500. PMID: 16554811
3. KCNQ1 K+ channel-mediated cardiac channelopathies.  |  Loussouarn, G., et al. 2006. Methods Mol Biol. 337: 167-83. PMID: 16929947
4. Skipping of Exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome.  |  Zehelein, J., et al. 2006. J Biol Chem. 281: 35397-403. PMID: 16987820
5. Beta-thalassaemia and sickle cell anaemia as paradigms of hypercoagulability.  |  Ataga, KI., et al. 2007. Br J Haematol. 139: 3-13. PMID: 17854302
6. The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3.  |  Berger, AC., et al. 2007. J Cell Sci. 120: 3640-52. PMID: 17895371
7. Wilms tumour: prognostic factors, staging, therapy and late effects.  |  Kaste, SC., et al. 2008. Pediatr Radiol. 38: 2-17. PMID: 18026723
8. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks.  |  Lee, JH. and Paull, TT. 2007. Oncogene. 26: 7741-8. PMID: 18066086
9. Targeted cancer therapies based on the inhibition of DNA strand break repair.  |  O'Connor, MJ., et al. 2007. Oncogene. 26: 7816-24. PMID: 18066095

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-C11orf24 Antibody (E-11) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-C11orf24 Antibody (E-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

C11orf24 Antibody (E-11) Specifications

Alternate Product Name: C11orf24

Product Clone Name: E-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 313-331

Epitope Target: C11orf24

Epitope Species: human

Product Reactivity/Detection: C11orf24 of human origin, 1810055G02Rik of mouse origin, and the corresponding rat homolog

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for C11orf24 Antibody (E-11): P: Blocking Peptide