c-Rel Antibody (B-4): sc-365694
- c-Rel Antibody (B-4) is a mouse monoclonal IgG3 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 489-524 within the C-terminus of c-Rel of human origin
- recommended for detection of c-Rel p75 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-365694 X, 200 µg/0.1 ml)
- See c-Rel (B-6): sc-6955 for c-Rel antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG3 BP-HRP is the preferred secondary detection reagent for c-Rel Antibody (B-4) for WB applications. This reagent is now offered in a bundle with c-Rel Antibody (B-4) (see ordering information below).
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c-Rel Antibody (B-4) is a mouse monoclonal IgG3 antibody that detects c-Rel in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). c-Rel is a vital member of the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) family, which plays a significant role in regulating immune responses and cell survival. c-Rel is primarily located in the cytoplasm of various cell types, where c-Rel is kept in an inactive form, but upon activation, c-Rel translocates to the nucleus to initiate the transcription of target genes involved in immune function and inflammation. Proper regulation of c-Rel is crucial, as dysregulation can lead to various diseases, including autoimmune disorders and cancers. Notably, c-Rel interacts with other proteins in the NFκB signaling pathway, such as p65 and p50, forming heterodimers that enhance the transcriptional activity of immune response genes. anti-c-Rel antibody (B-4) is an essential tool for researchers studying the intricate mechanisms of immune regulation and the potential therapeutic targets within the NFκB signaling cascade.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
c-Rel Antibody (B-4) | sc-365694 | 200 µg/ml | $322.00 | |||
c-Rel Antibody (B-4): m-IgG3 BP-HRP Bundle | sc-550436 | 200 µg Ab; 40 µg BP | $361.00 | |||
c-Rel (B-4) Neutralizing Peptide | sc-365694 P | 100 µg/0.5 ml | $69.00 | |||
c-Rel Antibody (B-4) X | sc-365694 X | 200 µg/0.1 ml | $322.00 |