c-Rel Inhibitors
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
BAY-11-7082 is a synthetic compound that inhibits NF-κB signaling by blocking the phosphorylation and degradation of its inhibitor, IκBα. By preventing IκBα degradation, it indirectly inhibits c-Rel translocation to the nucleus and its transcriptional activity on target genes. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a natural compound that can inhibit NF-κB activation by blocking IκB kinase (IKK) activity, preventing IκBα degradation, and thus interfering with c-Rel translocation to the nucleus and its transcriptional activity on target genes. | ||||||
BAY 11-7085 | 196309-76-9 | sc-202490 sc-202490A | 10 mg 50 mg | $124.00 $526.00 | 55 | |
Bay 11-7085 is a synthetic compound similar to BAY-11-7082 and acts as an NF-κB inhibitor by blocking the phosphorylation and degradation of IκBα. Its mechanism of action on c-Rel is likely similar to BAY-11-7082. | ||||||
Withaferin A | 5119-48-2 | sc-200381 sc-200381A sc-200381B sc-200381C | 1 mg 10 mg 100 mg 1 g | $130.00 $583.00 $4172.00 $20506.00 | 20 | |
Withaferin A is a natural compound that has been suggested to interfere with NF-κB signaling, possibly through inhibition of IKK activity. By blocking IκBα degradation, it indirectly affects c-Rel translocation to the nucleus and its transcriptional activity. | ||||||
Celastrol, Celastrus scandens | 34157-83-0 | sc-202534 | 10 mg | $158.00 | 6 | |
Celastrol is a natural compound that can inhibit NF-κB activation by interfering with the phosphorylation and degradation of IκBα. By preventing IκBα degradation, it indirectly inhibits c-Rel translocation to the nucleus and its transcriptional activity on target genes. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $81.00 $306.00 | 32 | |
Parthenolide is a natural compound that can inhibit NF-κB activation by blocking IKK activity, thus preventing IκBα degradation. This leads to the indirect inhibition of c-Rel translocation to the nucleus and its transcriptional activity. | ||||||
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $107.00 $416.00 $1248.00 | 35 | |
Leptomycin B is a natural compound that inhibits NF-κB nuclear translocation by blocking the exportin CRM1. By preventing nuclear translocation of NF-κB complexes, including c-Rel, it reduces their transcriptional activity on target genes. | ||||||
Dehydroandrographoline | 134418-28-3 | sc-280669 | 25 mg | $220.00 | ||
Dehydroandrographolide is a natural compound that can inhibit NF-κB activation by blocking IKK activity and preventing IκBα degradation. This leads to the indirect inhibition of c-Rel translocation to the nucleus and its transcriptional activity. | ||||||
Mangiferin | 4773-96-0 | sc-491041 | 10 mg | $140.00 | ||
Mangiferin is a natural compound that has been suggested to interfere with NF-κB signaling, possibly by blocking IKK activity and preventing IκBα degradation. It indirectly affects c-Rel translocation to the nucleus and its transcriptional activity. | ||||||
Naringin | 10236-47-2 | sc-203443 sc-203443A | 25 g 50 g | $45.00 $101.00 | 7 | |
Nimbolide is a natural compound that can inhibit NF-κB activation by interfering with the phosphorylation and degradation of IκBα. By preventing IκBα degradation, it indirectly inhibits c-Rel translocation to the nucleus and its transcriptional activity on target genes. | ||||||