Brn-2/BRN2/POU3F2 Antibody (A-11): sc-398966
- Brn-2/BRN2/POU3F2 Antibody (A-11) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 181-240 mapping within an internal region of Brn-2 of human origin
- recommended for detection of Brn-2 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-398966 X, 200 µg/0.1 ml)
- See Brn-2/BRN2/POU3F2 (B-2): sc-393324 for Brn-2/BRN2/POU3F2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Brn-2/BRN2/POU3F2 Antibody (A-11) for WB applications. These reagents are now offered in bundles with Brn-2/BRN2/POU3F2 Antibody (A-11) (see ordering information below).
Brn-2 Antibody (A-11) is a mouse monoclonal IgG2a antibody that detects Brn-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Brn-2 is a member of the Brn family of transcription factors, specifically classified as a class III POU domain protein, and plays a pivotal role in the development of the central nervous system, particularly during early embryonic stages. Brn-2 is predominantly expressed in the developing forebrain and is coexpressed in most layer II-V cortical neurons, where Brn-2 is essential for regulating the initiation of radial migration of cortical neurons. Proper function of Brn-2 is crucial, as Brn-2 not only influences neuronal development but also has implications in the differentiation of smooth muscle cells. Additionally, Brn-2 interacts with other transcription factors, which can modulate gene expression and contribute to various cellular processes. The ability of Brn-2 to bind to specific DNA sequences and regulate transcription underscores Brn-2′s importance in neurodevelopment and potential involvement in neurological disorders. With versatile applications and significant role in cellular development, anti-Brn-2 antibody (A-11) is an invaluable tool for researchers studying the complexities of neuronal differentiation and function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Brn-2/BRN2/POU3F2 Antibody (A-11) | sc-398966 | 200 µg/ml | $322.00 | |||
Brn-2/BRN2/POU3F2 Antibody (A-11): m-IgG Fc BP-HRP Bundle | sc-538553 | 200 µg Ab; 10 µg BP | $361.00 | |||
Brn-2/BRN2/POU3F2 Antibody (A-11): m-IgGκ BP-HRP Bundle | sc-536189 | 200 µg Ab; 40 µg BP | $361.00 | |||
Brn-2/BRN2/POU3F2 Antibody (A-11): m-IgG2a BP-HRP Bundle | sc-548338 | 200 µg Ab; 10 µg BP | $361.00 | |||
Brn-2/BRN2/POU3F2 Antibody (A-11) X | sc-398966 X | 200 µg/0.1 ml | $322.00 |