BRF2 Antibody (A-12): sc-271182
- BRF2 Antibody (A-12) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 371-405 at the C-terminus of BRF2 of human origin
- recommended for detection of BRF2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BRF2 Antibody (A-12) for WB applications. These reagents are now offered in bundles with BRF2 Antibody (A-12) (see ordering information below).
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BRF2 Antibody (A-12) is a mouse monoclonal IgG2a antibody that detects BRF2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BRF2 plays a crucial role in the transcriptional regulation of small nuclear RNAs, particularly in the recruitment of RNA polymerase III to type 3 promoters, such as the human U6 small nuclear RNA promoter. Unlike its counterpart BRF1, which forms a stable complex with TATA-binding protein, BRF2 does not establish a stable interaction with its components, which is significant for the dynamic regulation of transcription. This unique characteristic allows BRF2 to adapt to various cellular contexts, ensuring precise control over gene expression necessary for processes like cell growth and differentiation. BRF2 (A-12) antibody is an essential tool for researchers studying RNA polymerase III transcription mechanisms and their implications in cellular function and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BRF2 Antibody (A-12) | sc-271182 | 200 µg/ml | $322.00 | |||
BRF2 Antibody (A-12): m-IgG Fc BP-HRP Bundle | sc-537582 | 200 µg Ab; 10 µg BP | $361.00 | |||
BRF2 Antibody (A-12): m-IgGκ BP-HRP Bundle | sc-534887 | 200 µg Ab; 40 µg BP | $361.00 | |||
BRF2 Antibody (A-12): m-IgG2a BP-HRP Bundle | sc-548057 | 200 µg Ab; 10 µg BP | $361.00 | |||
BRF2 (A-12) Neutralizing Peptide | sc-271182 P | 100 µg/0.5 ml | $69.00 |