BMP-9 Antibody (H-3): sc-514211
- BMP-9 Antibody (H-3) is a mouse monoclonal IgG1 κ BMP-9 antibody, cited in 13 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 406-425 at the C-terminus of BMP-9 of human origin
- BMP-9 Antibody (H-3) is recommended for detection of precursor and mature BMP-9 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-BMP-9 Antibody (H-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BMP-9 Antibody (H-3) for WB applications. These reagents are now offered in bundles with BMP-9 Antibody (H-3) (see ordering information below).
BMP-9 Antibody (H-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects BMP-9 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-BMP-9 antibody (H-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Bone morphogenic protein-9 (BMP-9) is a critical member of the transforming growth factor-beta (TGF-beta) superfamily, known for its essential role in tissue morphogenesis, particularly in the development and maintenance of bone and connective tissues. BMP-9 is primarily secreted by liver cells and has been shown to interact with specific receptors that promote cell proliferation and regulate blood glucose levels, effects that are distinct from those induced by TGF-beta. Notably, BMP-9 is involved in various post-translational modifications, including glycosylation, which can influence stability and activity, thereby impacting therapeutic potential. Research indicates that BMP-9 can enhance bone formation in vivo, making BMP-9 a promising candidate for innovative treatments in regenerative medicine and bone-related disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
BMP-9 Antibody (H-3) References:
- BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1. | Majumdar, MK., et al. 2001. J Cell Physiol. 189: 275-84. PMID: 11748585
- An integrated functional genomics screening program reveals a role for BMP-9 in glucose homeostasis. | Chen, C., et al. 2003. Nat Biotechnol. 21: 294-301. PMID: 12598908
- Human mesenchymal stem cells transduced with recombinant bone morphogenetic protein-9 adenovirus promote osteogenesis in rodents. | Dayoub, H., et al. 2003. Tissue Eng. 9: 347-56. PMID: 12740097
- Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat. | Li, JZ., et al. 2003. Gene Ther. 10: 1735-43. PMID: 12939640
- Effects of BMP-9 and BMP-2 on the PI3K/Akt Pathway in MC3T3-E1 Preosteoblasts. | Lauzon, MA., et al. 2016. Tissue Eng Part A. 22: 1075-85. PMID: 27477105
- BMP-9 interferes with liver regeneration and promotes liver fibrosis. | Breitkopf-Heinlein, K., et al. 2017. Gut. 66: 939-954. PMID: 28336518
- BMP-9 Modulates the Hepatic Responses to LPS. | Gaitantzi, H., et al. 2020. Cells. 9: PMID: 32143367
- BMP-9 Improves the Osteogenic Differentiation Ability over BMP-2 through p53 Signaling In Vitro in Human Periosteum-Derived Cells. | Park, JH., et al. 2023. Int J Mol Sci. 24: PMID: 37894931
- Quality Over Quantity: BMP-9 Regulation of Scar Formation After Myocardial Infarction. | O'Donnell, A. and Yutzey, KE. 2023. JACC Basic Transl Sci. 8: 1331-1333. PMID: 38094690
- Disrupted BMP-9 Signaling Impairs Pulmonary Vascular Integrity in Hepatopulmonary Syndrome. | Robert, F., et al. 2024. Am J Respir Crit Care Med. 210: 648-661. PMID: 38626313
- BMP-9 mediates fibroproliferation in fibrodysplasia ossificans progressiva through TGF-β signaling. | Zhao, C., et al. 2025. EMBO Mol Med. 17: 112-128. PMID: 39627568
- Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation. | Song, JJ., et al. 1995. Endocrinology. 136: 4293-7. PMID: 7664647
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BMP-9 Antibody (H-3) | sc-514211 | 200 µg/ml | $322.00 | |||
BMP-9 Antibody (H-3): m-IgG Fc BP-HRP Bundle | sc-531065 | 200 µg Ab; 10 µg BP | $361.00 | |||
BMP-9 Antibody (H-3): m-IgGκ BP-HRP Bundle | sc-524648 | 200 µg Ab, 40 µg BP | $361.00 | |||
BMP-9 Antibody (H-3) AC | sc-514211 AC | 500 µg/ml, 25% agarose | $424.00 | |||
BMP-9 Antibody (H-3) HRP | sc-514211 HRP | 200 µg/ml | $322.00 | |||
BMP-9 Antibody (H-3) FITC | sc-514211 FITC | 200 µg/ml | $336.00 | |||
BMP-9 Antibody (H-3) PE | sc-514211 PE | 200 µg/ml | $349.00 | |||
BMP-9 Antibody (H-3) Alexa Fluor® 488 | sc-514211 AF488 | 200 µg/ml | $364.00 | |||
BMP-9 Antibody (H-3) Alexa Fluor® 546 | sc-514211 AF546 | 200 µg/ml | $364.00 | |||
BMP-9 Antibody (H-3) Alexa Fluor® 594 | sc-514211 AF594 | 200 µg/ml | $364.00 | |||
BMP-9 Antibody (H-3) Alexa Fluor® 647 | sc-514211 AF647 | 200 µg/ml | $364.00 | |||
BMP-9 Antibody (H-3) Alexa Fluor® 680 | sc-514211 AF680 | 200 µg/ml | $364.00 | |||
BMP-9 Antibody (H-3) Alexa Fluor® 790 | sc-514211 AF790 | 200 µg/ml | $364.00 | |||
BMP-9 (H-3) Neutralizing Peptide | sc-514211 P | 100 µg/0.5 ml | $69.00 |