beta Tubulin Antibody (TUB 2.1): sc-58886
- beta Tubulin Antibody (TUB 2.1) is a mouse monoclonal IgG1 κ, cited in 28 publications, provided at 200 µg/ml
- raised against purified brain β Tubulin of rat origin
- Anti-beta Tubulin Antibody (TUB 2.1) is recommended for detection of β Tubulin of mouse, rat, human and bovine origin by WB, IP, IF and IHC(P)
- Anti-beta Tubulin Antibody (TUB 2.1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of beta Tubulin (TUB 2.1): sc-58886.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for beta Tubulin Antibody (TUB 2.1) for WB and IHC(P) applications. These reagents are now offered in bundles with beta Tubulin Antibody (TUB 2.1) (see ordering information below).
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SEE ALSO...
β Tubulin Antibody (TUB 2.1) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect β Tubulin (β-TUB), also known as tubulin beta chain, across multiple species including mouse, rat, human, and bovine. β-TUB monoclonal antibody (TUB 2.1) is raised against purified brain β-TUB of rat origin, ensuring robust and precise binding in various applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. β-TUB is a fundamental component of the cytoskeleton, forming heterodimers with α Tubulin that assemble into microtubules, which are essential for maintaining cell shape, facilitating intracellular transport, and enabling accurate cell division. Post-translational modifications of β-TUB, including acetylation, detyrosination, and polyglutamylation, play critical roles in regulating microtubule stability and dynamics, as well as in modulating interactions with motor proteins like kinesin and dynein, thereby influencing processes such as intracellular trafficking and signal transduction. These modifications are crucial for the functional diversity and adaptability of microtubules in different cellular contexts and during various stages of the cell cycle. Additionally, β-TUB exists in multiple isoforms, such as β1, β2, β3, β4, β5, β6, and β8, each exhibiting unique expression patterns and functional roles, including the neuron-specific β3 isoform which is essential for neuronal development and function. Understanding the structural and functional nuances of β-TUB, including post-translational modifications, is essential for elucidating mechanisms underlying cellular architecture and the pathogenesis of diseases like cancer and neurodegenerative disorders. Anti-β-TUB antibody (TUB 2.1) is available in both non-conjugated forms and various conjugated forms, including horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for diverse experimental requirements.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
beta Tubulin Antibody (TUB 2.1) | sc-58886 | 200 µg/ml | $316.00 | |||
beta Tubulin Antibody (TUB 2.1): m-IgG Fc BP-HRP Bundle | sc-526917 | 200 µg Ab; 10 µg BP | $354.00 | |||
beta Tubulin Antibody (TUB 2.1): m-IgG1 BP-HRP Bundle | sc-532290 | 200 µg Ab; 20 µg BP | $354.00 | |||
beta Tubulin Antibody (TUB 2.1) AC | sc-58886 AC | 500 µg/ml, 25% agarose | $416.00 | |||
beta Tubulin Antibody (TUB 2.1) HRP | sc-58886 HRP | 200 µg/ml | $316.00 | |||
beta Tubulin Antibody (TUB 2.1) FITC | sc-58886 FITC | 200 µg/ml | $330.00 | |||
beta Tubulin Antibody (TUB 2.1) PE | sc-58886 PE | 200 µg/ml | $343.00 | |||
beta Tubulin Antibody (TUB 2.1) Alexa Fluor® 488 | sc-58886 AF488 | 200 µg/ml | $357.00 | |||
beta Tubulin Antibody (TUB 2.1) Alexa Fluor® 546 | sc-58886 AF546 | 200 µg/ml | $357.00 | |||
beta Tubulin Antibody (TUB 2.1) Alexa Fluor® 594 | sc-58886 AF594 | 200 µg/ml | $357.00 | |||
beta Tubulin Antibody (TUB 2.1) Alexa Fluor® 647 | sc-58886 AF647 | 200 µg/ml | $357.00 | |||
beta Tubulin Antibody (TUB 2.1) Alexa Fluor® 680 | sc-58886 AF680 | 200 µg/ml | $357.00 | |||
beta Tubulin Antibody (TUB 2.1) Alexa Fluor® 790 | sc-58886 AF790 | 200 µg/ml | $357.00 |