beta Tubulin Antibody (37): sc-101527

β Tubulin Antibody (37) is a mouse monoclonal IgG1 kappa light chain antibody engineered to recognize recombinant human β Tubulin, a pivotal protein within the cytoskeletal framework of eukaryotic cells. β Tubulin, also known as tubulin beta-1 chain or TUBB, pairs with α Tubulin to form heterodimers that polymerize into microtubules, essential for maintaining cell shape, facilitating intracellular transport, and ensuring accurate cell division. A key aspect of β Tubulin′s functionality is its post-translational modifications, such as tyrosination, detyrosination, acetylation, and polyglutamylation, which regulate microtubule stability, dynamics, and interactions with microtubule-associated proteins. These modifications are crucial for processes like mitosis, intracellular trafficking, and neuronal function, highlighting the importance of accurately detecting β Tubulin in various cellular contexts. Anti-β Tubulin antibody (37) demonstrates broad species reactivity, effectively recognizing β Tubulin in mouse, rat, and human samples, and is validated for use in western blotting (WB), immunoprecipitation (IP), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA) applications. β Tubulin (37) monoclonal antibody is an invaluable tool for studies investigating cytoskeletal dynamics, cell division mechanisms, and related disease processes where tubulin modifications play a critical role.

The preferred beta Tubulin antibody is beta Tubulin Antibody (D-10): sc-5274.