beta Actin Antibody (ACTBD11B7): sc-81178

β-Actin Antibody (ACTBD11B7) is a mouse monoclonal IgG1 kappa light chain antibody raised against a recombinant protein corresponding to a region near the C-terminus of human β-Actin. Specifically, anti-β-Actin antibody (ACTBD11B7) detects β-Actin of mouse, rat, and human origin and is suitable for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). β-Actin is a highly conserved cytoplasmic protein that plays a crucial role in maintaining cell structure, motility, and integrity as a fundamental component of the cytoskeleton. β-Actin is involved in various cellular processes such as cell division, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and shape. The dynamic organization of β-Actin is regulated by small GTPases like Rho, Rac, and Cdc42, which control the assembly of actin stress fibers, membrane ruffles, and filopodia, respectively. These interactions are essential for cytoskeletal reorganization and cellular responses to environmental cues. β-Actin interacts with numerous proteins including myosin motor proteins and components of the Arp2/3 complex, facilitating actin filament nucleation and movement. β-Actin is ubiquitously expressed in all eukaryotic cells and, along with γ-Actin, constitutes the principal actin isoforms in non-muscle tissues, while α-Actin is predominantly found in muscle cells. Given its essential functions and constant expression levels, β-Actin serves as a loading control in protein assays to ensure equal protein loading across samples, making anti-β-Actin antibody (ACTBD11B7) a valuable tool for researchers studying cytoskeletal dynamics, cell motility, and related signaling pathways.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-beta Actin Antibody (ACTBD11B7) has 1,081 citations in a variety of scientific publications.

Primary antibodies like Anti-beta Actin Antibody (ACTBD11B7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

beta Actin Antibody (ACTBD11B7) Specifications

Alternate Product Name: β-Actin

Product Clone Name: ACTBD11B7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: β-Actin

Epitope Species: human

Product Reactivity/Detection: β-Actin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 1.0% stabilizer protein

Research Citations: 1,081 citations in various scientific publications

Available Conjugates/Forms for beta Actin Antibody (ACTBD11B7): N/A

The preferred beta Actin antibody is beta Actin Antibody (C4): sc-47778.