Bet1L Antibody (19): sc-135846

Bet1L Antibody (19) is a mouse monoclonal IgG1 kappa light chain antibody that detects Bet1L protein of mouse, rat, human, and canine origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-Bet1L antibody (19) is available as the non-conjugated format, providing researchers with a reliable tool for studying this critical protein. Bet1L, also known as GS15, plays a vital role in the SNARE complex, which is essential for membrane fusion processes within the cell. Specifically, Bet1L interacts with syntaxin 5, GS28, and Ykt6 to facilitate the trafficking of proteins within the Golgi apparatus, a key organelle involved in modifying, sorting, and packaging proteins for secretion or delivery to other organelles. Proper functioning of Bet1L and associated SNARE proteins is crucial for maintaining cellular homeostasis, as disruptions in vesicular transport can lead to various diseases, including neurodegenerative disorders and cancer. Bet1L (19) monoclonal antibody enables researchers to gain insights into the mechanisms of vesicular transport and the implications of Bet1L in cellular function and disease pathology.

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Bet1L Antibody (19) References:

1. Subunit structure of a mammalian ER/Golgi SNARE complex.  |  Xu, D., et al. 2000. J Biol Chem. 275: 39631-9. PMID: 11035026
2. GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus.  |  Xu, Y., et al. 2002. Mol Biol Cell. 13: 3493-507. PMID: 12388752
3. The SNARE motif contributes to rbet1 intracellular targeting and dynamics independently of SNARE interactions.  |  Joglekar, AP., et al. 2003. J Biol Chem. 278: 14121-33. PMID: 12566453
4. Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack.  |  Volchuk, A., et al. 2004. Mol Biol Cell. 15: 1506-18. PMID: 14742712
5. Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network.  |  Tai, G., et al. 2004. Mol Biol Cell. 15: 4011-22. PMID: 15215310
6. COG-7-deficient Human Fibroblasts Exhibit Altered Recycling of Golgi Proteins.  |  Steet, R. and Kornfeld, S. 2006. Mol Biol Cell. 17: 2312-21. PMID: 16510524
7. The syntaxin family of vesicular transport receptors.  |  Bennett, MK., et al. 1993. Cell. 74: 863-73. PMID: 7690687
8. Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus.  |  Hay, JC., et al. 1996. J Biol Chem. 271: 5671-9. PMID: 8621431

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Bet1L Antibody (19) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-Bet1L Antibody (19) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Bet1L Antibody (19) Specifications

Alternate Product Name: Bet1L

Product Clone Name: 19

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-85

Epitope Target: Bet1L

Epitope Species: rat

Product Reactivity/Detection: Bet1L

Species Reactivity/Detection: mouse, rat, human, canine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Bet1L Antibody (19): N/A