Bax Antibody (6D149): sc-70405
- Bax Antibody (6D149) is a mouse monoclonal IgG1 κ, cited in 15 publications, provided at 200 µg/ml
- recommended for detection of Bax of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
- available conjugated to agarose for IP; and to phycoerythrin for IF, IHC(P) and FCM
- See Bax (B-9): sc-7480 for Bax antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Bax Antibody (6D149) for WB and IHC(P) applications. These reagents are now offered in bundles with Bax Antibody (6D149) (see ordering information below).
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Bax Antibody (6D149) is a mouse monoclonal IgG1 antibody that detects Bax in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and flow cytometry (FCM). Bax plays a crucial role in the regulation of apoptosis, acting as a pro-apoptotic member of the Bcl-2 protein family. Bax (6D149) antibody helps identify Bax′s primary function to promote cell death in response to cellular stress and damage, which is vital for maintaining tissue homeostasis and preventing the proliferation of damaged cells that could lead to cancer. Bax is predominantly localized in the cytosol under normal conditions but translocates to the mitochondria in response to apoptotic signals, where Bax facilitates the release of cytochrome c and other pro-apoptotic factors, thereby triggering the apoptotic cascade. The balance between Bax and its anti-apoptotic counterpart, Bcl-2, is essential for determining cell fate, making Bax a significant target for therapeutic interventions in cancer and other diseases characterized by dysregulated apoptosis. Anti-Bax antibody (6D149) provides a reliable tool for researchers studying apoptosis and its implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bax Antibody (6D149) | sc-70405 | 200 µg/ml | $316.00 | |||
Bax Antibody (6D149): m-IgG Fc BP-HRP Bundle | sc-539272 | 200 µg Ab; 10 µg BP | $354.00 | |||
Bax Antibody (6D149): m-IgG1 BP-HRP Bundle | sc-541370 | 200 µg Ab; 20 µg BP | $354.00 | |||
Bax Antibody (6D149) AC | sc-70405 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Bax Antibody (6D149) PE | sc-70405 PE | 200 µg/ml | $343.00 |