Bax Antibody (6A7): sc-23959
- Bax Antibody (6A7) is a mouse monoclonal IgG1 κ, cited in 268 publications, provided at 200 µg/ml
- raised against the N-terminal residues 12-24 common to human, mouse,and rat Bax protein
- Anti-Bax Antibody (6A7) is recommended for detection of Bax of mouse, rat and human origin by WB, IP, IF and IHC(P)
- Anti-Bax Antibody (6A7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Bax Antibody (6A7) for WB and IHC(P) applications. This reagent is now offered in a bundle with Bax Antibody (6A7) (see ordering information below).
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Bax Antibody (6A7) is a mouse monoclonal IgG1 kappa light chain antibody that detects Bax in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Bax (6A7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. Bax protein plays a critical role in the regulation of apoptosis, acting as a pro-apoptotic member of the Bcl-2 protein family. Bax function is vital for maintaining cellular homeostasis, as Bax promotes cell death in response to stress signals, thereby preventing the proliferation of damaged or potentially cancerous cells. Bax is primarily localized to the outer mitochondrial membrane, where Bax facilitates the release of cytochrome c, a key step in the apoptotic pathway. The balance between Bax and anti-apoptotic counterpart, Bcl-2, is crucial for determining cell fate, and dysregulation of this balance can lead to various diseases, including cancer. Using anti-Bax antibody (6A7) in research can provide insights into apoptosis mechanisms and Bax role in cellular stress responses, contributing to a better understanding of therapeutic targets in cancer and other diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bax Antibody (6A7) | sc-23959 | 200 µg/ml | $322.00 | |||
Bax Antibody (6A7): m-IgG Fc BP-HRP Bundle | sc-525510 | 200 µg Ab; 10 µg BP | $361.00 | |||
Bax Antibody (6A7) AC | sc-23959 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Bax Antibody (6A7) HRP | sc-23959 HRP | 200 µg/ml | $322.00 | |||
Bax Antibody (6A7) FITC | sc-23959 FITC | 200 µg/ml | $336.00 | |||
Bax Antibody (6A7) PE | sc-23959 PE | 200 µg/ml | $349.00 | |||
Bax Antibody (6A7) Alexa Fluor® 488 | sc-23959 AF488 | 200 µg/ml | $364.00 | |||
Bax Antibody (6A7) Alexa Fluor® 546 | sc-23959 AF546 | 200 µg/ml | $364.00 | |||
Bax Antibody (6A7) Alexa Fluor® 594 | sc-23959 AF594 | 200 µg/ml | $364.00 | |||
Bax Antibody (6A7) Alexa Fluor® 647 | sc-23959 AF647 | 200 µg/ml | $364.00 | |||
Bax Antibody (6A7) Alexa Fluor® 680 | sc-23959 AF680 | 200 µg/ml | $364.00 | |||
Bax Antibody (6A7) Alexa Fluor® 790 | sc-23959 AF790 | 200 µg/ml | $364.00 |