BAP1 Antibody (F-6): sc-48386
- BAP1 Antibody (F-6) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 430-729 of BAP1 of human origin
- recommended for detection of BAP1 of mouse, rat and human origin by WB, IP, IF and ELISA
- See BAP1 (C-4): sc-28383 for BAP1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BAP1 Antibody (F-6) for WB applications. These reagents are now offered in bundles with BAP1 Antibody (F-6) (see ordering information below).
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BAP1 Antibody (F-6) is a mouse monoclonal IgG2a antibody that detects BAP1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BAP1, or BRCA1-associated protein 1, is a crucial protein that functions as a ubiquitin hydrolase, playing a significant role in the regulation of protein degradation and cellular signaling pathways. This function is vital for maintaining cellular homeostasis and preventing tumorigenesis, as BAP1 helps to modulate the activity of various substrates involved in cell cycle regulation and DNA repair. The interaction of BAP1 with BRCA1 is particularly important, as BAP1 enhances BRCA1-mediated cell growth suppression, thereby contributing to the tumor-suppressive functions of the BRCA1-BAP1 complex. Additionally, BAP1 interacts with several other proteins, including the histone deubiquitinase complex, which further underscores BAP1′s role in epigenetic regulation and cancer biology. Anti-BAP1 antibody (F-6) is an essential tool for researchers studying the mechanisms of cancer development and the intricate pathways involved in tumor suppression.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BAP1 Antibody (F-6) | sc-48386 | 200 µg/ml | $322.00 | |||
BAP1 Antibody (F-6): m-IgG Fc BP-HRP Bundle | sc-536823 | 200 µg Ab; 10 µg BP | $361.00 | |||
BAP1 Antibody (F-6): m-IgGκ BP-HRP Bundle | sc-533990 | 200 µg Ab; 40 µg BP | $361.00 | |||
BAP1 Antibody (F-6): m-IgG2a BP-HRP Bundle | sc-547877 | 200 µg Ab; 10 µg BP | $361.00 |