B lymphocytes Antibody (Lym-1): sc-69676

B lymphocytes Antibody (Lym-1) is a mouse monoclonal IgG2a kappa light chain antibody that detects B lymphocytes protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). B lymphocytes (Lym-1) antibody is available in both non-conjugated and various conjugated forms, including phycoerythrin (PE) and fluorescein isothiocyanate (FITC), providing flexibility for different experimental needs. B lymphocytes are crucial components of the adaptive immune system, primarily responsible for the humoral immune response, which is vital for the production of antibodies against pathogens. These cells are characterized by unique B cell receptors (BCRs), which are membrane-bound immunoglobulins that specifically bind to antigens, allowing for activation and differentiation of B lymphocytes into antibody-secreting plasma cells. The ability of B lymphocytes to generate a diverse array of antibodies is essential for the immune system′s capacity to recognize and neutralize a wide variety of pathogens. Furthermore, the interaction of B lymphocytes with helper T cells is critical for activation and subsequent antibody production, highlighting the importance of these cells in orchestrating an effective immune response. B lymphocytes (Lym-1) monoclonal antibody serves as a valuable tool for researchers studying the dynamics of B cell activation, differentiation, and function in various immunological contexts.

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B lymphocytes Antibody (Lym-1) References:

1. Positive and negative selection during B lymphocyte development.  |  Monroe, JG., et al. 2003. Immunol Res. 27: 427-42. PMID: 12857986
2. PI3K signaling controls cell fate at many points in B lymphocyte development and activation.  |  Donahue, AC. and Fruman, DA. 2004. Semin Cell Dev Biol. 15: 183-97. PMID: 15209378
3. Immune system learning and memory quantified by graphical analysis of B-lymphocyte phylogenetic trees.  |  Dunn-Walters, DK., et al. 2004. Biosystems. 76: 141-55. PMID: 15351138
4. B lymphocyte signaling pathways in systemic autoimmunity: implications for pathogenesis and treatment.  |  Zouali, M. and Sarmay, G. 2004. Arthritis Rheum. 50: 2730-41. PMID: 15457440
5. Regulation of B lymphocyte activation by complement C3 and the B cell coreceptor complex.  |  Rickert, RC. 2005. Curr Opin Immunol. 17: 237-43. PMID: 15886112
6. Nicotinic receptors regulate B lymphocyte activation and immune response.  |  Skok, M., et al. 2005. Eur J Pharmacol. 517: 246-51. PMID: 15963492
7. CD22: a multifunctional receptor that regulates B lymphocyte survival and signal transduction.  |  Tedder, TF., et al. 2005. Adv Immunol. 88: 1-50. PMID: 16227086
8. Primary HIV-1 infection sets the stage for important B lymphocyte dysfunctions.  |  Titanji, K., et al. 2005. AIDS. 19: 1947-55. PMID: 16260900
9. A new antigen identified by the monoclonal antibody UCHB 1 delivers a costimulatory signal to a subset of human B cells.  |  Armitage, RJ., et al. 1988. Eur J Immunol. 18: 67-76. PMID: 3257923

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-B lymphocytes Antibody (Lym-1) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-B lymphocytes Antibody (Lym-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

B lymphocytes Antibody (Lym-1) Specifications

Alternate Product Name: B lymphocytes

Product Clone Name: Lym-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids:

Epitope Target: B lymphocytes

Epitope Species: human

Product Reactivity/Detection: HLA-DR10 and B cell lymphomas

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for B lymphocytes Antibody (Lym-1): FITC: Fluoroscein, PE: Phycoerythrin