AVP Receptor V1a Antibody (7G8): sc-134276

AVP Receptor V1a Antibody (7G8) is a mouse monoclonal IgG2a antibody that detects AVP Receptor V1a in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). AVP Receptor V1a plays a crucial role in various physiological processes, including blood vessel constriction, liver glycogenolysis, and platelet adhesion, making AVP Receptor V1a essential for maintaining vascular tone and regulating blood pressure. AVP Receptor V1a is primarily located on the cell membrane and is coupled to Gq/11 proteins, which facilitate an increase in intracellular calcium concentration, thereby triggering downstream signaling pathways that influence these vital functions. AVP Receptor V1a is expressed in several tissues, including vascular smooth muscle and platelets, highlighting AVP Receptor V1a′s importance in cardiovascular health. Additionally, AVP Receptor V1a exists in both full-length and truncated forms due to proteolytic cleavage, which can impact functional activity and regulatory mechanisms. Understanding the dynamics of AVP Receptor V1a is critical, as AVP Receptor V1a is implicated in various pathophysiological conditions, including hypertension and heart failure, making AVP Receptor V1a a potential target for therapeutic intervention.

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AVP Receptor V1a Antibody (7G8) References:

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