ATF-1/ATF1 Antibody (H-3): sc-365525
- ATF-1/ATF1 Antibody (H-3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-60 mapping at the N-terminus of ATF-1 of human origin
- recommended for detection of ATF-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- TransCruz reagent for ChIP application (sc-365525 X, 200 µg/0.1 ml)
- See ATF-1/ATF1 (25C10G): sc-270 for ATF-1/ATF1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ATF-1/ATF1 Antibody (H-3) for WB and IHC(P) applications. These reagents are now offered in bundles with ATF-1/ATF1 Antibody (H-3) (see ordering information below).
ATF-1 Antibody (H-3) is a mouse monoclonal IgG1 antibody that detects ATF-1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ATF-1, a member of the ATF/CREB transcription factor family, plays a crucial role in regulating gene expression in response to cellular signals, particularly through interaction with the cAMP response element (CRE). ATF-1 is primarily located in the nucleus, where binding to DNA influences transcription of target genes, making ATF-1 essential for processes such as cell growth, differentiation, and response to stress. ATF-1′s ability to form homodimers and heterodimers with other proteins, such as c-Jun, enhances transcriptional activity, thereby amplifying cellular response to various stimuli. Additionally, ATF-1 undergoes post-translational modifications, including phosphorylation, which is vital for activation and function; for instance, phosphorylation at specific threonine residues is necessary for transcriptional activation, highlighting the importance of these modifications in regulating activity and stability. With diverse roles in cellular signaling and gene regulation, ATF-1 is a key player in maintaining cellular homeostasis and responding to environmental changes, making anti-ATF-1 antibody (H-3) an invaluable tool for researchers studying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ATF-1/ATF1 Antibody (H-3) | sc-365525 | 200 µg/ml | $322.00 | |||
ATF-1/ATF1 Antibody (H-3): m-IgG Fc BP-HRP Bundle | sc-537812 | 200 µg Ab; 10 µg BP | $361.00 | |||
ATF-1/ATF1 Antibody (H-3): m-IgGκ BP-HRP Bundle | sc-535215 | 200 µg Ab; 40 µg BP | $361.00 | |||
ATF-1/ATF1 Antibody (H-3): m-IgG1 BP-HRP Bundle | sc-545371 | 200 µg Ab; 20 µg BP | $361.00 | |||
ATF-1/ATF1 Antibody (H-3) X | sc-365525 X | 200 µg/0.1 ml | $322.00 |