ATF-1/ATF1 Antibody (2A9/8): sc-53172
- ATF-1/ATF1 Antibody (2A9/8) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- raised against recombinant ATF1 of S. pombe origin
- recommended for detection of ATF-1 of mouse, rat, human and S. pombe origin by WB and IP
- See ATF-1/ATF1 (25C10G): sc-270 for ATF-1/ATF1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ATF-1/ATF1 Antibody (2A9/8) for WB applications. These reagents are now offered in bundles with ATF-1/ATF1 Antibody (2A9/8) (see ordering information below).
ATF-1 Antibody (2A9/8) is a mouse monoclonal IgG2a antibody that detects ATF-1 in mouse, rat, human, and S. pombe by western blotting (WB) and immunoprecipitation (IP). ATF-1 is a crucial member of the ATF/CREB transcription factor family, which plays a significant role in regulating gene expression in response to various cellular signals. ATF-1 is primarily located in the nucleus, where ATF-1 binds to specific DNA sequences known as cAMP response elements (CRE) to modulate transcription. Nuclear localization of ATF-1 is vital for function, as ATF-1 interacts with other transcriptional regulators and chromatin remodeling complexes, thereby influencing the transcription of target genes involved in processes such as cell growth, differentiation, and stress responses. Notably, ATF-1′s ability to form homodimers and heterodimers with other family members, such as ATF-2 and c-Jun, enhances transcriptional activity and expands regulatory potential. Furthermore, ATF-1 is phosphorylated by protein kinase A (PKA), which is essential for activation and subsequent gene regulation. ATF-1 (2A9/8) monoclonal antibody is an invaluable tool for researchers studying the intricate mechanisms of gene regulation and the role of ATF-1 in various biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ATF-1/ATF1 Antibody (2A9/8) | sc-53172 | 200 µg/ml | $322.00 | |||
ATF-1/ATF1 Antibody (2A9/8): m-IgG Fc BP-HRP Bundle | sc-536902 | 200 µg Ab; 10 µg BP | $361.00 | |||
ATF-1/ATF1 Antibody (2A9/8): m-IgGκ BP-HRP Bundle | sc-534074 | 200 µg Ab; 40 µg BP | $361.00 | |||
ATF-1/ATF1 Antibody (2A9/8): m-IgG2a BP-HRP Bundle | sc-547897 | 200 µg Ab; 10 µg BP | $361.00 |