ATE1 Antibody (H-12): sc-271219
- ATE1 Antibody (H-12) is a mouse monoclonal IgG2a κ, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of ATE1 of human origin
- recommended for detection of ATE1 isoforms 1 and 2 of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG2a BP-HRP is the preferred secondary detection reagent for ATE1 Antibody (H-12) for WB and IHC(P) applications. This reagent is now offered in a bundle with ATE1 Antibody (H-12) (see ordering information below).
QUICK LINKS
SEE ALSO...
ATE1 Antibody (H-12) is a mouse monoclonal IgG2a antibody that detects Arginyl-tRNA-protein transferase (ATE1) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ATE1, also known as arginyltransferase 1, is a crucial enzyme belonging to the R-transferase family, responsible for posttranslational modification of proteins through arginine addition to N-terminal specific substrates, particularly those containing aspartate, glutamate, and possibly cysteine. This modification is essential for subsequent ubiquitin-mediated protein degradation, highlighting ATE1′s significant role in cellular protein turnover and quality control. ATE1 consists of 518 amino acids and exists in two distinct isoforms due to alternative splicing, with the monomeric form capable of localizing to both cytoplasm and nucleus. Understanding ATE1′s function and interactions is vital for elucidating mechanisms of protein regulation and degradation, which are critical for maintaining cellular homeostasis and responding to stress.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ATE1 Antibody (H-12) | sc-271219 | 200 µg/ml | $322.00 | |||
ATE1 Antibody (H-12): m-IgG2a BP-HRP Bundle | sc-546034 | 200 µg Ab; 10 µg BP | $361.00 |