AsnRS Antibody (A-1): sc-271058

AsnRS Antibody (A-1) is a mouse monoclonal IgG1 antibody that detects AsnRS (cytoplasmic Asparaginyl-tRNA synthetase) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AsnRS plays a crucial role in protein synthesis by catalyzing the attachment of asparagine to its corresponding tRNA, ensuring the accurate translation of genetic information into functional proteins. This process is vital for cellular function, as the fidelity of tRNA charging directly impacts the synthesis of proteins that are essential for various biological processes. AsnRS′s ability to perform proofreading reactions further enhances the accuracy of protein synthesis, preventing the incorporation of incorrect amino acids that could lead to dysfunctional proteins. Additionally, AsnRS autoantibodies have been linked to interstitial lung disease, highlighting AsnRS′s significance in both normal physiology and disease states. Anti-AsnRS antibody (A-1) is an invaluable tool for researchers studying the mechanisms of protein synthesis and the implications of AsnRS in various health conditions.

The preferred AsnRS antibody is AsnRS Antibody (G-8): sc-271059.