ARP Antibody (H-6): sc-515907

ARP Antibody (H-6) is a mouse monoclonal IgG2b antibody that detects arginine-rich protein (ARP) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARP is a highly conserved protein encoded by a gene located on human chromosome 3p21, and mutations in ARP have been implicated in various human tumors, including primary head and neck, non-small-cell lung, renal cell, breast, and prostate cancers. Notably, while earlier studies suggested that variations in the triplet AGG repeat around codon 50 contributed to malignancy, more recent research has indicated that these variations do not significantly differ between normal and cancer patient populations. Instead, research has discovered that ARP features a smaller N-terminal region that excludes the arginine-rich segment, with codon 50 serving as the actual start codon for the protein. Despite ARP′s association with cancer, the precise function remains to be elucidated, highlighting the need for further investigation into ARP′s biological role and potential implications in tumorigenesis. Anti-ARP antibody (H-6) is an essential tool for researchers aiming to explore the complexities of ARP and its involvement in cancer biology.

The preferred ARP antibody is ARP Antibody (B-3): sc-515906.