ARP-1 Antibody (C-10): sc-393481
- ARP-1 Antibody (C-10) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 156-181 near the N-terminus of ARP-1 of human origin
- recommended for detection of ARP-1 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, porcine and avian
- TransCruz reagent for ChIP application (sc-393481 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ARP-1 Antibody (C-10) for WB applications. These reagents are now offered in bundles with ARP-1 Antibody (C-10) (see ordering information below).
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SEE ALSO...
ARP-1 Antibody (C-10) is a mouse monoclonal IgG1 antibody that detects ARP-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARP-1, also known as COUP-TFII, plays a crucial role in various biological processes, particularly in gene expression regulation during development. ARP-1 is primarily located in the nucleus, where ARP-1 functions as a transcription factor modulating the activity of other nuclear receptors, including retinoic acid receptors and peroxisome proliferator-activated receptors. ARP-1′s interaction with these receptors is vital for maintaining proper cellular functions, influencing pathways related to metabolism, differentiation, and development. ARP-1′s expression is tightly regulated in different tissues, particularly in the developing and central nervous systems, highlighting ARP-1′s importance in neural development and differentiation. Anti-ARP-1 antibody (C-10) enables researchers to gain insights into ARP-1′s regulatory mechanisms and impact on various physiological processes, making anti-ARP-1 antibody (C-10) an essential tool for studies in developmental biology and related fields.
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ARP-1 Antibody (C-10) References:
- Multiple roles of COUP-TFII in cancer initiation and progression. | Litchfield, LM. and Klinge, CM. 2012. J Mol Endocrinol. 49: R135-48. PMID: 22966133
- Suppression of COUP-TFII upregulates angiogenin and promotes angiogenesis in endometriosis. | Fu, JL., et al. 2018. Hum Reprod. 33: 1517-1527. PMID: 29982401
- The Coup-TFII orphan nuclear receptor is an activator of the γ-globin gene. | Fugazza, C., et al. 2021. Haematologica. 106: 474-482. PMID: 32107331
- An early start of Coup-TFII promotes γ-globin gene expression in adult erythroid cells. | Bottardi, S. and Milot, E. 2021. Haematologica. 106: 335-336. PMID: 33522785
- Orphan nuclear receptor COUP-TFII enhances myofibroblast glycolysis leading to kidney fibrosis. | Li, L., et al. 2021. EMBO Rep. 22: e51169. PMID: 34031962
- The nuclear receptors SF1 and COUP-TFII cooperate on the Insl3 promoter in Leydig cells. | Di-Luoffo, M., et al. 2022. Reproduction. 164: 31-40. PMID: 35666805
- An NKX-COUP-TFII morphogenetic code directs mucosal endothelial addressin expression. | Dinh, TT., et al. 2022. Nat Commun. 13: 7448. PMID: 36460642
- COUP-TFII regulates early bipotential gonad signaling and commitment to ovarian progenitors. | Ferreira, LGA., et al. 2024. Cell Biosci. 14: 3. PMID: 38178246
- A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. | Ben-Shushan, E., et al. 1995. Mol Cell Biol. 15: 1034-48. PMID: 7823919
- Functional domains of the human orphan receptor ARP-1/COUP-TFII involved in active repression and transrepression. | Achatz, G., et al. 1997. Mol Cell Biol. 17: 4914-32. PMID: 9271371
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARP-1 Antibody (C-10) | sc-393481 | 200 µg/ml | $322.00 | |||
ARP-1 Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-538229 | 200 µg Ab; 10 µg BP | $361.00 | |||
ARP-1 Antibody (C-10): m-IgGκ BP-HRP Bundle | sc-535799 | 200 µg Ab; 40 µg BP | $361.00 | |||
ARP-1 Antibody (C-10): m-IgG1 BP-HRP Bundle | sc-545590 | 200 µg Ab; 20 µg BP | $361.00 | |||
ARP-1 (C-10) Neutralizing Peptide | sc-393481 P | 100 µg/0.5 ml | $69.00 | |||
ARP-1 Antibody (C-10) X | sc-393481 X | 200 µg/0.1 ml | $322.00 |