ARMC7 Antibody (G-11): sc-515317
- ARMC7 Antibody (G-11) is a mouse monoclonal IgG1 κ ARMC7 antibody provided at 200 µg/ml
- raised against amino acids 1-118 mapping at the N-terminus of ARMC7 of human origin
- ARMC7 Antibody (G-11) is recommended for detection of ARMC7 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ARMC7 Antibody (G-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ARMC7 Antibody (G-11) for WB applications. These reagents are now offered in bundles with ARMC7 Antibody (G-11) (see ordering information below).
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ARMC7 Antibody (G-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects ARMC7 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARMC7 (G-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ARMC7, also known as armadillo repeat containing 7, consists of 198 amino acids and features two armadillo (ARM) repeats, which are critical for binding activity and interactions with other proteins. ARMC7 is conserved across a wide range of species, including chimpanzees, dogs, cows, mice, rats, chickens, zebrafish, Arabidopsis thaliana, and rice, highlighting fundamental biological importance. ARMC7 has been implicated in cancer-specific methylation, although precise biological role remains to be fully elucidated. ARMC7 gene is located on human chromosome 17q25.1, a region associated with several genetic disorders, including neurofibromatosis, which is characterized by neural and epidermal lesions and dysregulated Schwann cell growth. Additionally, chromosome 17 is linked to other conditions such as Alexander disease, Birt-Hogg-Dube syndrome, and Canavan disease, underscoring potential significance in various pathological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ARMC7 Antibody (G-11) References:
- Birt-Hogg-Dubé Syndrome. | Welsch, MJ., et al. 2005. Int J Dermatol. 44: 668-73. PMID: 16101870
- Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells. | Shen, Y., et al. 2006. Hum Mol Genet. 15: 2623-35. PMID: 16870691
- Neurofibromatosis 1, and Not TP53, seems to be the main target of chromosome 17 deletions in de novo acute myeloid leukemia. | Suela, J., et al. 2007. J Clin Oncol. 25: 1151-2; author reply 1152-3. PMID: 17369586
- Quantification of N-acetylaspartic acid in urine by LC-MS/MS for the diagnosis of Canavan disease. | Al-Dirbashi, OY., et al. 2007. J Inherit Metab Dis. 30: 612. PMID: 17632691
- Genetic causes of brain tumors: neurofibromatosis, tuberous sclerosis, von Hippel-Lindau, and other syndromes. | Farrell, CJ. and Plotkin, SR. 2007. Neurol Clin. 25: 925-46, viii. PMID: 17964021
- Novel deletion mutation in GFAP gene in an infantile form of Alexander disease. | Murakami, N., et al. 2008. Pediatr Neurol. 38: 50-2. PMID: 18054694
- Genome-wide promoter analysis uncovers portions of the cancer methylome. | Hoque, MO., et al. 2008. Cancer Res. 68: 2661-70. PMID: 18413733
- Methylation markers for CCNA1 and C13ORF18 are strongly associated with high-grade cervical intraepithelial neoplasia and cervical cancer in cervical scrapings. | Yang, N., et al. 2009. Cancer Epidemiol Biomarkers Prev. 18: 3000-7. PMID: 19843677
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARMC7 Antibody (G-11) | sc-515317 | 200 µg/ml | $316.00 | |||
ARMC7 Antibody (G-11): m-IgG Fc BP-HRP Bundle | sc-531336 | 200 µg Ab; 10 µg BP | $354.00 | |||
ARMC7 Antibody (G-11): m-IgGκ BP-HRP Bundle | sc-525001 | 200 µg Ab, 40 µg BP | $354.00 | |||
ARMC7 Antibody (G-11): m-IgG1 BP-HRP Bundle | sc-544491 | 200 µg Ab; 20 µg BP | $354.00 | |||
ARMC7 Antibody (G-11) AC | sc-515317 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ARMC7 Antibody (G-11) HRP | sc-515317 HRP | 200 µg/ml | $316.00 | |||
ARMC7 Antibody (G-11) FITC | sc-515317 FITC | 200 µg/ml | $330.00 | |||
ARMC7 Antibody (G-11) PE | sc-515317 PE | 200 µg/ml | $343.00 | |||
ARMC7 Antibody (G-11) Alexa Fluor® 488 | sc-515317 AF488 | 200 µg/ml | $357.00 | |||
ARMC7 Antibody (G-11) Alexa Fluor® 546 | sc-515317 AF546 | 200 µg/ml | $357.00 | |||
ARMC7 Antibody (G-11) Alexa Fluor® 594 | sc-515317 AF594 | 200 µg/ml | $357.00 | |||
ARMC7 Antibody (G-11) Alexa Fluor® 647 | sc-515317 AF647 | 200 µg/ml | $357.00 | |||
ARMC7 Antibody (G-11) Alexa Fluor® 680 | sc-515317 AF680 | 200 µg/ml | $357.00 | |||
ARMC7 Antibody (G-11) Alexa Fluor® 790 | sc-515317 AF790 | 200 µg/ml | $357.00 |