ARID3A Antibody (A-4): sc-398367
- ARID3A Antibody (A-4) is a mouse monoclonal IgG1 κ ARID3A antibody, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 565-592 at the C-terminus of ARID3A of human origin
- ARID3A Antibody (A-4) is recommended for detection of ARID3A of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ARID3A Antibody (A-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-398367 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ARID3A Antibody (A-4) for WB applications. These reagents are now offered in bundles with ARID3A Antibody (A-4) (see ordering information below).
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ARID3A Antibody (A-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects ARID3A protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ARID3A antibody (A-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ARID3A protein, also known as DRIL1 in humans and Bright in mice, plays a crucial role in the regulation of gene expression during development, particularly in differentiating cells of the gut and salivary glands. ARID3A′s unique structure includes an A/T-rich DNA-binding domain and a tetramerization domain, which are essential for function as a transcriptional activator. ARID3A′s ability to bind to specific DNA sequences allows regulation of genes involved in cell proliferation and differentiation, making ARID3A vital for normal cellular processes. Additionally, ARID3A gene is associated with Peutz-Jeghers syndrome, an autosomal-dominant disorder that increases the risk of various neoplasms, including gastrointestinal cancer. Notably, E2FBP1, which shares identity with ARID3A in the carboxy terminal region, regulates transcription factors involved in cell proliferation, highlighting the interconnectedness of these proteins in cellular regulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ARID3A Antibody (A-4) References:
- E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity. | DeGregori, J., et al. 1995. Genes Dev. 9: 2873-87. PMID: 7498785
- Mutually exclusive interaction of a novel matrix attachment region binding protein and the NF-muNR enhancer repressor. Implications for regulation of immunoglobulin heavy chain expression. | Zong, RT. and Scheuermann, RH. 1995. J Biol Chem. 270: 24010-8. PMID: 7592598
- The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. | Herrscher, RF., et al. 1995. Genes Dev. 9: 3067-82. PMID: 8543152
- Characterization of the dead ringer gene identifies a novel, highly conserved family of sequence-specific DNA-binding proteins. | Gregory, SL., et al. 1996. Mol Cell Biol. 16: 792-9. PMID: 8622680
- Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p. | Amos, CI., et al. 1997. Cancer Res. 57: 3653-6. PMID: 9288765
- The human dead ringer/bright homolog, DRIL1: cDNA cloning, gene structure, and mapping to D19S886, a marker on 19p13.3 that is strictly linked to the Peutz-Jeghers syndrome. | Kortschak, RD., et al. 1998. Genomics. 51: 288-92. PMID: 9722953
- A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer. | Suzuki, M., et al. 1998. Oncogene. 17: 853-65. PMID: 9780002
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARID3A Antibody (A-4) | sc-398367 | 200 µg/ml | $322.00 | |||
ARID3A Antibody (A-4): m-IgG Fc BP-HRP Bundle | sc-530776 | 200 µg Ab; 10 µg BP | $361.00 | |||
ARID3A Antibody (A-4): m-IgGκ BP-HRP Bundle | sc-524313 | 200 µg Ab, 40 µg BP | $361.00 | |||
ARID3A Antibody (A-4): m-IgG1 BP-HRP Bundle | sc-544248 | 200 µg Ab; 20 µg BP | $361.00 | |||
ARID3A Antibody (A-4) X | sc-398367 X | 200 µg/0.1 ml | $322.00 | |||
ARID3A Antibody (A-4) AC | sc-398367 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ARID3A Antibody (A-4) HRP | sc-398367 HRP | 200 µg/ml | $322.00 | |||
ARID3A Antibody (A-4) FITC | sc-398367 FITC | 200 µg/ml | $336.00 | |||
ARID3A Antibody (A-4) PE | sc-398367 PE | 200 µg/ml | $349.00 | |||
ARID3A Antibody (A-4) Alexa Fluor® 488 | sc-398367 AF488 | 200 µg/ml | $364.00 | |||
ARID3A Antibody (A-4) Alexa Fluor® 546 | sc-398367 AF546 | 200 µg/ml | $364.00 | |||
ARID3A Antibody (A-4) Alexa Fluor® 594 | sc-398367 AF594 | 200 µg/ml | $364.00 | |||
ARID3A Antibody (A-4) Alexa Fluor® 647 | sc-398367 AF647 | 200 µg/ml | $364.00 | |||
ARID3A Antibody (A-4) Alexa Fluor® 680 | sc-398367 AF680 | 200 µg/ml | $364.00 | |||
ARID3A Antibody (A-4) Alexa Fluor® 790 | sc-398367 AF790 | 200 µg/ml | $364.00 | |||
ARID3A (A-4) Neutralizing Peptide | sc-398367 P | 100 µg/0.5 ml | $69.00 |