ARHGAP19 Antibody (B-11): sc-398428
- ARHGAP19 Antibody (B-11) is a mouse monoclonal IgG1 κ ARHGAP19 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 388-401 within an internal region of ARHGAP19 of human origin
- ARHGAP19 Antibody (B-11) is recommended for detection of ARHGAP19 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ARHGAP19 Antibody (B-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ARHGAP19 Antibody (B-11) for WB applications. These reagents are now offered in bundles with ARHGAP19 Antibody (B-11) (see ordering information below).
ARHGAP19 Antibody (B-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects ARHGAP19 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ARHGAP19 antibody (B-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ARHGAP19 consists of 494 amino acids, is primarily localized in the nucleus and features a Rho-GAP domain that plays a crucial role in regulating Rho-type GTPases. By accelerating the intrinsic rate of GTP hydrolysis, ARHGAP19 functions as a negative regulator, converting active GTP-bound Rho proteins into their inactive GDP-bound state. This regulatory mechanism is vital for controlling cellular processes such as proliferation, migration, and differentiation, as well as actin remodeling, which are essential for maintaining normal cellular functions and responses to external stimuli. ARHGAP19 is strongly expressed in fetal liver, lung, brain, heart, kidney, and pancreas, while lower levels are found in adult ovary, spleen, and thymus. The gene encoding ARHGAP19 is located on human chromosome 10 and gives rise to multiple alternatively spliced isoforms, highlighting its potential complexity and functional diversity in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ARHGAP19 Antibody (B-11) References:
- Rho-family GTPases: it's not only Rac and Rho (and I like it). | Wennerberg, K. and Der, CJ. 2004. J Cell Sci. 117: 1301-12. PMID: 15020670
- Characterization of human ARHGAP10 gene in silico. | Katoh, M. and Katoh, M. 2004. Int J Oncol. 25: 1201-6. PMID: 15375573
- Identification and characterization of ARHGAP27 gene in silico. | Katoh, Y. and Katoh, M. 2004. Int J Mol Med. 14: 943-7. PMID: 15492870
- Rho GTPase activating proteins in cancer phenotypes. | Kandpal, RP. 2006. Curr Protein Pept Sci. 7: 355-65. PMID: 16918449
- Sequence analysis of a human RhoGAP domain-containing gene and characterization of its expression in human multiple tissues. | Lv, L., et al. 2007. DNA Seq. 18: 184-9. PMID: 17454002
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARHGAP19 Antibody (B-11) | sc-398428 | 200 µg/ml | $316.00 | |||
ARHGAP19 Antibody (B-11): m-IgG Fc BP-HRP Bundle | sc-530792 | 200 µg Ab; 10 µg BP | $354.00 | |||
ARHGAP19 Antibody (B-11): m-IgGκ BP-HRP Bundle | sc-524335 | 200 µg Ab, 40 µg BP | $354.00 | |||
ARHGAP19 Antibody (B-11): m-IgG1 BP-HRP Bundle | sc-544255 | 200 µg Ab; 20 µg BP | $354.00 | |||
ARHGAP19 Antibody (B-11) AC | sc-398428 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ARHGAP19 Antibody (B-11) HRP | sc-398428 HRP | 200 µg/ml | $316.00 | |||
ARHGAP19 Antibody (B-11) FITC | sc-398428 FITC | 200 µg/ml | $330.00 | |||
ARHGAP19 Antibody (B-11) PE | sc-398428 PE | 200 µg/ml | $343.00 | |||
ARHGAP19 Antibody (B-11) Alexa Fluor® 488 | sc-398428 AF488 | 200 µg/ml | $357.00 | |||
ARHGAP19 Antibody (B-11) Alexa Fluor® 546 | sc-398428 AF546 | 200 µg/ml | $357.00 | |||
ARHGAP19 Antibody (B-11) Alexa Fluor® 594 | sc-398428 AF594 | 200 µg/ml | $357.00 | |||
ARHGAP19 Antibody (B-11) Alexa Fluor® 647 | sc-398428 AF647 | 200 µg/ml | $357.00 | |||
ARHGAP19 Antibody (B-11) Alexa Fluor® 680 | sc-398428 AF680 | 200 µg/ml | $357.00 | |||
ARHGAP19 Antibody (B-11) Alexa Fluor® 790 | sc-398428 AF790 | 200 µg/ml | $357.00 | |||
ARHGAP19 (B-11) Neutralizing Peptide | sc-398428 P | 100 µg/0.5 ml | $68.00 |