ARH3 Antibody (D-2): sc-514545
- ARH3 Antibody (D-2) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 89-110 within an internal region of ARH3 of human origin
- recommended for detection of ARH3 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgGκ BP-HRP is the preferred secondary detection reagent for ARH3 Antibody (D-2) for WB applications. This reagent is now offered in a bundle with ARH3 Antibody (D-2) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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ARH3 Antibody (D-2) is a mouse monoclonal IgG1 antibody that detects ARH3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARH3, also known as ADP-ribosylhydrolase 3 or ADPRHL2, is a 363 amino acid protein that plays a crucial role in cellular processes by localizing to mitochondria, the cytoplasm, and the nucleus. ARH3 is a member of the ADP-ribosylglycohydrolase family and utilizes magnesium as a cofactor to catalyze the hydrolysis of poly(ADP-ribose), a modification that occurs following DNA damage. By generating ADP-ribose from poly(ADP-ribose), ARH3 is essential for maintaining normal neuronal cell function, which is vital for overall cellular health and response to stress. The gene encoding ARH3 is located on human chromosome 1, a region that spans 260 million base pairs and contains over 3,000 genes, many of which are associated with various diseases, including familial adenomatous polyposis and Parkinson′s disease. Aberrations in chromosome 1 are implicated in several cancers, highlighting the importance of ARH3 in both normal physiology and disease states. Anti-ARH3 antibody (D-2) is an invaluable tool for researchers studying the intricate roles of ARH3 in cellular function and pathology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARH3 Antibody (D-2) | sc-514545 | 200 µg/ml | $322.00 | |||
ARH3 Antibody (D-2): m-IgGκ BP-HRP Bundle | sc-552178 | 200 µg Ab; 40 µg BP | $361.00 | |||
ARH3 (D-2) Neutralizing Peptide | sc-514545 P | 100 µg/0.5 ml | $69.00 |