ARG1/Arginase 1 Antibody (A-2): sc-365547
- ARG1/Arginase 1 Antibody (A-2) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
- raised against amino acids 271-322 of Arginase 1 of human origin
- ARG1/Arginase 1 Antibody (A-2) is recommended for detection of Arginase 1 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ARG1/Arginase 1 Antibody (A-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ARG1/Arginase 1 Antibody (A-2) for WB and IHC(P) applications. These reagents are now offered in bundles with ARG1/Arginase 1 Antibody (A-2) (see ordering information below).
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Arginase 1 Antibody (A-2) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect human Arginase 1 with exceptional precision across various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Arginase 1 monoclonal antibody (A-2) targets an epitope spanning amino acids 271-322 of human Arginase 1, ensuring robust and selective binding to the target protein. Arginase 1, also called ARG1, AI, Arg-1, and PGIF, is predominantly expressed in the liver, and is a critical enzyme in the urea cycle, catalyzing the hydrolysis of arginine into ornithine and urea, which is essential for the detoxification of ammonia and the maintenance of nitrogen balance in the body. Structurally, Arginase 1 functions as a homotrimeric protein, with each monomer containing a binuclear manganese cluster that is vital for enzymatic activity. Beyond primary enzymatic role, Arginase 1 undergoes various post-translational modifications (PTMs) such as phosphorylation and acetylation, which are crucial for regulating activity, stability, and interaction with other cellular proteins. These PTMs play a significant role in modulating Arginase 1′s function in metabolic pathways, influencing processes like wound healing, immune response modulation, and cancer progression. Understanding these modifications provides insights into the regulation of arginine metabolism and involvement in various physiological and pathological conditions. Anti-Arginase 1 antibody (A-2) is available in both non-conjugated and multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, offering versatile options for researchers to investigate Arginase 1 in diverse experimental settings.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARG1/Arginase 1 Antibody (A-2) | sc-365547 | 200 µg/ml | $322.00 | |||
ARG1/Arginase 1 Antibody (A-2): m-IgG Fc BP-HRP Bundle | sc-527378 | 200 µg Ab; 10 µg BP | $361.00 | |||
ARG1/Arginase 1 Antibody (A-2): m-IgG1 BP-HRP Bundle | sc-532751 | 200 µg Ab; 20 µg BP | $361.00 | |||
ARG1/Arginase 1 Antibody (A-2) AC | sc-365547 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ARG1/Arginase 1 Antibody (A-2) HRP | sc-365547 HRP | 200 µg/ml | $322.00 | |||
ARG1/Arginase 1 Antibody (A-2) FITC | sc-365547 FITC | 200 µg/ml | $336.00 | |||
ARG1/Arginase 1 Antibody (A-2) PE | sc-365547 PE | 200 µg/ml | $349.00 | |||
ARG1/Arginase 1 Antibody (A-2) Alexa Fluor® 488 | sc-365547 AF488 | 200 µg/ml | $364.00 | |||
ARG1/Arginase 1 Antibody (A-2) Alexa Fluor® 546 | sc-365547 AF546 | 200 µg/ml | $364.00 | |||
ARG1/Arginase 1 Antibody (A-2) Alexa Fluor® 594 | sc-365547 AF594 | 200 µg/ml | $364.00 | |||
ARG1/Arginase 1 Antibody (A-2) Alexa Fluor® 647 | sc-365547 AF647 | 200 µg/ml | $364.00 | |||
ARG1/Arginase 1 Antibody (A-2) Alexa Fluor® 680 | sc-365547 AF680 | 200 µg/ml | $364.00 | |||
ARG1/Arginase 1 Antibody (A-2) Alexa Fluor® 790 | sc-365547 AF790 | 200 µg/ml | $364.00 |