ARD Antibody (A-8): sc-398680
- ARD Antibody (A-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 36-62 within an internal region of ARD of human origin
- recommended for detection of ARD of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ARD Antibody (A-8) for WB applications. These reagents are now offered in bundles with ARD Antibody (A-8) (see ordering information below).
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ARD Antibody (A-8) is a mouse monoclonal IgG1 antibody that detects acireductone dioxygenase (ARD) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARD is a 179 amino acid protein that plays a vital role in the L-methionine biosynthetic pathway, catalyzing the conversion of (S)-methyl-5-thio-alpha-D-ribose 1-phosphate to L-methionine, a process essential for protein synthesis and cellular function. ARD predominantly localizes in the nucleus and the cytoplasmic side of the cell membrane, suggesting a dual role in both gene regulation and cellular signaling. ARD expression occurs in various tissues, including the brain, heart, lung, colon, liver, kidney, spleen, and skeletal muscle, highlighting importance in multiple physiological processes. Additionally, ARD interacts with membrane-type matrix metalloproteinase 1 (MT-MMP-1), potentially modulating cell migration, which is crucial in developmental and pathological contexts. Multiple isoforms of ARD arise from alternative splicing, allowing for functional diversity and adaptability in response to cellular needs. Anti-ARD antibody (A-8) serves as an invaluable tool for researchers investigating the intricate roles of ARD in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARD Antibody (A-8) | sc-398680 | 200 µg/ml | $322.00 | |||
ARD Antibody (A-8): m-IgG Fc BP-HRP Bundle | sc-538499 | 200 µg Ab; 10 µg BP | $361.00 | |||
ARD Antibody (A-8): m-IgGκ BP-HRP Bundle | sc-536125 | 200 µg Ab; 40 µg BP | $361.00 | |||
ARD Antibody (A-8): m-IgG1 BP-HRP Bundle | sc-545732 | 200 µg Ab; 20 µg BP | $361.00 | |||
ARD (A-8) Neutralizing Peptide | sc-398680 P | 100 µg/0.5 ml | $69.00 |