API5 Antibody (Z-18): sc-101203
- API5 Antibody (Z-18) is a mouse monoclonal IgG2b κ provided at 100 µg/ml
- raised against recombinant API5 of human origin
- recommended for detection of API5 of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for API5 Antibody (Z-18). This work is in progress.
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SEE ALSO...
API5 Antibody (Z-18) is a mouse monoclonal IgG2b antibody that detects API5 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). API5, also known as apoptosis inhibitor 5, plays a crucial role in regulating apoptosis, which is the process of programmed cell death essential for maintaining cellular homeostasis and development. Anti-API5 antibody (Z-18) contributes to studying tumor progression and malignancy, making API5 a significant factor in cancer biology. API5 is primarily localized in the nucleus, where API5 forms complexes with other proteins, such as fibroblast growth factor 2 (FGF-2), thereby influencing FGF-2-dependent signaling pathways. This nuclear localization enables API5 to act as a transcription regulator, modulating the expression of genes involved in cell survival and proliferation. The presence of specific structural motifs within API5, such as the nuclear localization sequence and the leucine zipper domain, further underscores API5′s importance in cellular signaling and transcriptional regulation. Given API5′s association with various cancer cell lines and role in promoting cell survival, API5 remains a key target for research into therapeutic strategies aimed at combating cancer.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
API5 Antibody (Z-18) | sc-101203 | 100 µg/ml | $339.00 |