Antiquitin Antibody (C-4): sc-365642
- Antiquitin Antibody (C-4) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 489-506 at the C-terminus of Antiquitin of human origin
- recommended for detection of Antiquitin of human and avian origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and avian
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Antiquitin Antibody (C-4) for WB and IHC(P) applications. These reagents are now offered in bundles with Antiquitin Antibody (C-4) (see ordering information below).
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SEE ALSO...
Antiquitin Antibody (C-4) is a mouse monoclonal IgG2b antibody that detects Antiquitin in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Antiquitin, also known as ALDH7A1, is a 539 amino acid protein that plays a crucial role in the detoxification of aldehydes, particularly those derived from lipid peroxidation and alcohol metabolism. Antiquitin is predominantly expressed in tissues such as the ovary, heart, eye, kidney, and ear, highlighting its importance in maintaining cellular health and function. The structure of Antiquitin contains a highly conserved aldehyde dehydrogenase domain, which is essential for enzymatic activity in converting toxic aldehydes into less harmful acids. This enzymatic function is vital for preventing cellular damage and maintaining metabolic balance, particularly in tissues that are highly susceptible to oxidative stress. Mutations in the gene encoding Antiquitin can lead to pyridoxine-dependent epilepsy, a rare but severe neurological disorder characterized by early-onset seizures and associated complications. Anti-Antiquitin antibody (C-4) provides a valuable tool for researchers studying the role of Antiquitin in health and disease, enabling insights into its function and the consequences of its dysregulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Antiquitin Antibody (C-4) | sc-365642 | 200 µg/ml | $322.00 | |||
Antiquitin Antibody (C-4): m-IgGκ BP-HRP Bundle | sc-535230 | 200 µg Ab; 40 µg BP | $361.00 | |||
Antiquitin Antibody (C-4): m-IgG2b BP-HRP Bundle | sc-549373 | 200 µg Ab; 10 µg BP | $361.00 | |||
Antiquitin (C-4) Neutralizing Peptide | sc-365642 P | 100 µg/0.5 ml | $69.00 |