Anti-Ankyrin G Antibody (463) is a mouse monoclonal IgG1 (kappa light chain) Ankyrin G antibody provided at 200 µg/ml
raised against a synthetic peptide derived from the spectrin-binding domain of Ankyrin G human origin
Anti-Ankyrin G Antibody (463) is recommended for detection of Ankyrin G of mouse, rat and human origin by WB, IP, IF and IHC(P); also reactive with additional species, including canine
Anti-Ankyrin G Antibody (463) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Ankyrin G (463): sc-12719.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Ankyrin G Antibody (463) is a high quality monoclonal Ankyrin G antibody (also designated Ankyrin 3 antibody, or ANK3 antibody) suitable for the detection of the Ankyrin G protein of mouse, rat and human origin. Ankyrin G Antibody (463) is available as both the non-conjugated anti-Ankyrin G antibody form, as well as multiple conjugated forms of anti-Ankyrin G antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Members of the Ankyrin family of proteins mediate the attachment of integral membrane proteins to the cytoskeleton. ANK1, ANK2 and ANK3 genes encode for the proteins in this family, Ankyrin-1 (also designated Ankyrin R), Ankyrin B and Ankyrin G, respectively. The proteins are structured similarly, each composed of an N-terminal domain with multiple ankyrin repeats, a highly conserved central spectrin binding domain and C-terminal regulatory domains which are susceptible to the most variance. Both Ankyrin B and Ankyrin G are essential for normal neuronal functions. Ankyrin G was originally identified localized to the nodes of Ranvier and axon initial segments where it was found to mediate normal neuronal sodium channel function. Ankyrin G, named for its giant size and general expression, exhibits tissue-specific alternative mRNA processing. The two largest protein isoforms are expressed only in nervous tissue, with additional smaller isoforms found in an array of other tissues including lung, kidney, spleen, liver and heart.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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