ANKRD7 Antibody (B-9): sc-515170
- ANKRD7 Antibody (B-9) is a mouse monoclonal IgG2b κ ANKRD7 antibody provided at 200 µg/ml
- raised against amino acids 1-59 mapping at the N-terminus of ANKRD7 of human origin
- ANKRD7 Antibody (B-9) is recommended for detection of ANKRD7 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ANKRD7 Antibody (B-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP is the preferred secondary detection reagent for ANKRD7 Antibody (B-9) for WB and IHC(P) applications. This reagent is now offered in a bundle with ANKRD7 Antibody (B-9) (see ordering information below).
ANKRD7 Antibody (B-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects ANKRD7 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ANKRD7 (B-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ANKRD7 protein, also known as testis-specific protein TSA806, is a 254 amino acid protein characterized by five ankyrin repeats, which are crucial for its role as a membrane adaptor molecule. These ankyrin repeats facilitate coupling of integral membrane proteins to the spectrin-based cytoskeleton network, a process vital for maintaining cell shape and stability. Expression of ANKRD7 is predominantly localized in the testis, where ANKRD7 exists in two isoforms generated through alternative splicing, highlighting specific functional roles in reproductive biology. The gene encoding ANKRD7 is located on human chromosome 7, a chromosome associated with various genetic disorders, including Osteogenesis imperfecta and Pendred syndrome, underscoring the importance of ANKRD7 in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ANKRD7 Antibody (B-9) References:
- Ankyrins, multifunctional proteins involved in many cellular pathways. | Hryniewicz-Jankowska, A., et al. 2002. Folia Histochem Cytobiol. 40: 239-49. PMID: 12219834
- The DNA sequence of human chromosome 7. | Hillier, LW., et al. 2003. Nature. 424: 157-64. PMID: 12853948
- Lissencephaly 1 linking to multiple diseases: mental retardation, neurodegeneration, schizophrenia, male sterility, and more. | Reiner, O., et al. 2006. Neuromolecular Med. 8: 547-65. PMID: 17028375
- Diversity in membrane binding sites of ankyrins. Brain ankyrin, erythrocyte ankyrin, and processed erythrocyte ankyrin associate with distinct sites in kidney microsomes. | Davis, J., et al. 1989. J Biol Chem. 264: 6417-26. PMID: 2522931
- Ankyrin and synapsin: spectrin-binding proteins associated with brain membranes. | Bennett, V., et al. 1985. J Cell Biochem. 29: 157-69. PMID: 2933418
- Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method. | Ozaki, K., et al. 1996. Genomics. 36: 316-9. PMID: 8812458
- Molecular anatomy of chromosome 7q deletions in myeloid neoplasms: evidence for multiple critical loci. | Liang, H., et al. 1998. Proc Natl Acad Sci U S A. 95: 3781-5. PMID: 9520444
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ANKRD7 Antibody (B-9) | sc-515170 | 200 µg/ml | $322.00 | |||
ANKRD7 Antibody (B-9): m-IgG2b BP-HRP Bundle | sc-548811 | 200 µg Ab; 10 µg BP | $361.00 | |||
ANKRD7 Antibody (B-9) AC | sc-515170 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ANKRD7 Antibody (B-9) HRP | sc-515170 HRP | 200 µg/ml | $322.00 | |||
ANKRD7 Antibody (B-9) FITC | sc-515170 FITC | 200 µg/ml | $336.00 | |||
ANKRD7 Antibody (B-9) PE | sc-515170 PE | 200 µg/ml | $349.00 | |||
ANKRD7 Antibody (B-9) Alexa Fluor® 488 | sc-515170 AF488 | 200 µg/ml | $364.00 | |||
ANKRD7 Antibody (B-9) Alexa Fluor® 546 | sc-515170 AF546 | 200 µg/ml | $364.00 | |||
ANKRD7 Antibody (B-9) Alexa Fluor® 594 | sc-515170 AF594 | 200 µg/ml | $364.00 | |||
ANKRD7 Antibody (B-9) Alexa Fluor® 647 | sc-515170 AF647 | 200 µg/ml | $364.00 | |||
ANKRD7 Antibody (B-9) Alexa Fluor® 680 | sc-515170 AF680 | 200 µg/ml | $364.00 | |||
ANKRD7 Antibody (B-9) Alexa Fluor® 790 | sc-515170 AF790 | 200 µg/ml | $364.00 |