ANKRD32 Antibody (G-1): sc-514264

ANKRD32 Antibody (G-1) is a mouse monoclonal IgM antibody that detects ANKRD32 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ANKRD32 antibody (G-1) is available as the non-conjugated form. ANKRD32 protein, also known as BRCTD1, consists of 1,058 amino acids and features three ankyrin repeats and two BRCT domains. ANKRD32 mediates protein-protein interactions and is involved in various cellular signaling pathways. ANKRD32 is located in the cytoplasm and associates with the cytoskeleton, maintaining cell shape and facilitating intracellular transport. Mutations or deletions in ANKRD32 can lead to severe genetic disorders, including periventricular heterotopia, mental retardation, and epilepsy, highlighting ANKRD32′s importance in neurodevelopmental processes. ANKRD32 is located on human chromosome 5q15, a region critical for various biological functions and conserved across multiple species, including chimpanzees, dogs, cows, mice, rats, and chickens. Deletion of chromosome 5q14.3-q15, which encompasses ANKRD32, has been linked to significant health issues, underscoring ANKRD32′s importance in both normal physiology and disease states.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

ANKRD32 Antibody (G-1) References:

1. Homozygous deletion scanning of the lung cancer genome at a 100-kb resolution.  |  Nagayama, K., et al. 2007. Genes Chromosomes Cancer. 46: 1000-10. PMID: 17674361
2. Global gene expression analysis of early response to chemotherapy treatment in ovarian cancer spheroids.  |  L'Espérance, S., et al. 2008. BMC Genomics. 9: 99. PMID: 18302766
3. Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles.  |  Bertucci, F., et al. 2008. Oncogene. 27: 5359-72. PMID: 18490921
4. Periventricular heterotopia, mental retardation, and epilepsy associated with 5q14.3-q15 deletion.  |  Cardoso, C., et al. 2009. Neurology. 72: 784-92. PMID: 19073947
5. Sexually dimorphic gene expression in the chick brain before gonadal differentiation.  |  Lee, SI., et al. 2009. Poult Sci. 88: 1003-15. PMID: 19359689
6. Integrated genomic and transcriptional analysis of the in vitro evolution of telomerase-immortalized urothelial cells (TERT-NHUC).  |  Chapman, EJ., et al. 2009. Genes Chromosomes Cancer. 48: 694-710. PMID: 19405089
7. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.  |  Scott, LJ., et al. 2009. Proc Natl Acad Sci U S A. 106: 7501-6. PMID: 19416921

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ANKRD32 Antibody (G-1) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ANKRD32 Antibody (G-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ANKRD32 Antibody (G-1) Specifications

Alternate Product Name: ANKRD32

Product Clone Name: G-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 95-118

Epitope Target: ANKRD32

Epitope Species: human

Product Reactivity/Detection: ANKRD32

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ANKRD32 Antibody (G-1): P: Blocking Peptide