Angiotensin I Antibody (BGN/KA/22H): sc-80682
- Angiotensin I Antibody (BGN/KA/22H) is a mouse monoclonal IgG2b, cited in 1 publications, provided at 100 µg/ml
- raised against Angiotensin I of human origin
- recommended for detection of Angiotensin I of human origin by and ELISA; non cross-reactive with angiotensinogen, angiotensin II or angiotensin III
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Angiotensin I Antibody (BGN/KA/22H). This work is in progress.
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Angiotensin I Antibody (BGN/KA/22H) is a mouse monoclonal IgG2b antibody that detects Angiotensin I in human samples through enzyme-linked immunosorbent assay (ELISA). Anti-Angiotensin I antibody (BGN/KA/22H) serves as a crucial tool for studying a key component of the renin-angiotensin system, which plays a significant role in regulating blood pressure and fluid balance in the body. Angiotensin I is produced from angiotensinogen, a precursor synthesized in the liver, and is subsequently converted into Angiotensin II by the action of the angiotensin-converting enzyme (ACE). This conversion is vital as Angiotensin II is a potent vasoconstrictor that not only elevates blood pressure but also stimulates the release of aldosterone, promoting sodium retention and increasing blood volume. The regulation of Angiotensin I and its conversion to Angiotensin II is essential for maintaining cardiovascular homeostasis, and dysregulation of this pathway can lead to hypertension and other cardiovascular diseases. Angiotensin I monoclonal antibody (BGN/KA/22H) provides researchers with an invaluable tool for studying the dynamics of this critical hormone and its implications in various physiological and pathological conditions.
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Angiotensin I Antibody (BGN/KA/22H) References:
- Angiotensin I, angiotensin II and their biologically active peptides. | Ferrario, CM. 2002. J Hypertens. 20: 805-7. PMID: 12011630
- Properties and distribution of angiotensin I converting enzyme. | Igić, R. and Behnia, R. 2003. Curr Pharm Des. 9: 697-706. PMID: 12570787
- Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion. | Gonzalez-Villalobos, RA., et al. 2011. J Am Soc Nephrol. 22: 449-59. PMID: 21115616
- Human monocyte subsets exhibit divergent angiotensin I-converting activity. | Rutkowska-Zapała, M., et al. 2015. Clin Exp Immunol. 181: 126-32. PMID: 25707554
- Tissue Specificity of Human Angiotensin I-Converting Enzyme. | Kryukova, OV., et al. 2015. PLoS One. 10: e0143455. PMID: 26600189
- Bioavailability of Orally Administered Des-Aspartate-Angiotensin I in Human Subjects. | Lee, KO., et al. 2018. Drugs R D. 18: 51-54. PMID: 29168127
- Cryo-EM reveals mechanisms of angiotensin I-converting enzyme allostery and dimerization. | Lubbe, L., et al. 2022. EMBO J. 41: e110550. PMID: 35818993
- LC/MS/MS assessment of changes in placental angiotensin I metabolism in preeclampsia. | Stettner-Kołodziejska, D., et al. 2022. Folia Med Cracov. 62: 71-88. PMID: 36088594
- The granulocyte-angiotensin system. Angiotensin I-converting activity of cathepsin G. | Klickstein, LB., et al. 1982. J Biol Chem. 257: 15042-6. PMID: 6294088
- Plasma active renin, angiotensin I, and angiotensin II during pregnancy and in preeclampsia. | Langer, B., et al. 1998. Obstet Gynecol. 91: 196-202. PMID: 9469275
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Angiotensin I Antibody (BGN/KA/22H) | sc-80682 | 100 µg/ml | $322.00 |