Angiotensin Inhibitors
Items 1 to 10 of 20 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Candesartan | 139481-59-7 | sc-217825 sc-217825B sc-217825A | 10 mg 100 mg 1 g | $46.00 $92.00 $148.00 | 6 | |
Candesartan is a selective angiotensin II receptor antagonist that exhibits unique binding characteristics, particularly at the AT1 receptor. Its structure allows for high affinity and specificity, leading to conformational changes in the receptor that inhibit downstream signaling pathways. This modulation affects vascular smooth muscle contraction and aldosterone secretion. The compound's lipophilic nature enhances its membrane permeability, influencing its distribution and interaction with biological membranes. | ||||||
Losartan | 114798-26-4 | sc-353662 | 100 mg | $127.00 | 18 | |
Losartan is a direct inhibitor of the renin-angiotensin system (RAS) by selectively blocking angiotensin II type 1 receptors. By doing so, it prevents the vasoconstrictive and aldosterone-releasing effects of angiotensin II, contributing to blood pressure regulation. Losartan is widely used for hypertension and associated cardiovascular conditions. | ||||||
Tranilast | 53902-12-8 | sc-200389 sc-200389A sc-200389B sc-200389C | 10 mg 50 mg 1 g 5 g | $30.00 $101.00 $277.00 $959.00 | 2 | |
Tranilast functions as an angiotensin modulator, exhibiting unique interactions with the angiotensin II receptor. Its distinct molecular structure facilitates competitive inhibition, altering receptor conformation and disrupting typical signaling cascades. This compound demonstrates a notable affinity for specific binding sites, influencing downstream effects on cellular processes. Additionally, its hydrophilic properties enhance solubility, impacting its kinetic behavior in various environments. | ||||||
Candesartan-d5 | 1189650-58-5 | sc-217827 | 1 mg | $373.00 | ||
Candesartan-d5 acts as an angiotensin antagonist, characterized by its selective binding to angiotensin II receptors. Its deuterated structure enhances stability and alters isotopic labeling, providing insights into metabolic pathways. The compound exhibits unique kinetic profiles, influencing receptor desensitization and internalization. Its lipophilic nature contributes to membrane permeability, affecting distribution and interaction dynamics within cellular environments. | ||||||
RHC-80267 | 83654-05-1 | sc-222251 | 10 mg | $75.00 | 1 | |
RHC-80267 functions as an angiotensin analog, exhibiting a high affinity for angiotensin receptors. Its unique structural features facilitate specific hydrogen bonding interactions, enhancing receptor activation. The compound's distinct electronic properties influence its reactivity and stability in biological systems. Additionally, RHC-80267 demonstrates varied solubility profiles, impacting its distribution in different environments and altering its interaction kinetics with target proteins. | ||||||
Candesartan Ethyl Ester | 139481-58-6 | sc-211008 | 10 mg | $280.00 | ||
Candesartan Ethyl Ester acts as an angiotensin receptor antagonist, characterized by its unique hydrophobic regions that promote selective binding. The compound's stereochemistry allows for specific conformational changes upon receptor engagement, influencing downstream signaling pathways. Its lipophilic nature enhances membrane permeability, while its metabolic stability is attributed to strategic functional group placements, affecting its degradation kinetics in various environments. | ||||||
Candesartan Methyl Ester-d5 | sc-217826 | 1 mg | $300.00 | |||
Candesartan Methyl Ester-d5 exhibits distinctive interactions with angiotensin receptors, facilitated by its deuterated methyl ester moiety, which enhances isotopic stability. This compound's unique electronic distribution influences its affinity and selectivity, allowing for nuanced modulation of receptor conformation. The presence of deuterium alters reaction kinetics, potentially impacting metabolic pathways and interactions with enzymes, while its solubility characteristics suggest favorable behavior in diverse chemical environments. | ||||||
Angiotensin II [Sar1 Ile8] | 67724-27-0 | sc-391239 sc-391239A | 5 mg 10 mg | $151.00 $215.00 | ||
Angiotensin II [Sar1 Ile8] is a modified peptide that exhibits unique binding dynamics with angiotensin receptors, characterized by its specific amino acid substitutions. These alterations enhance its stability and receptor affinity, promoting distinct signaling pathways. The compound's structural modifications influence its conformational flexibility, allowing for varied interactions with downstream effectors. Additionally, its hydrophilic properties facilitate solvation in biological systems, impacting its distribution and activity. | ||||||
moexipril | 103775-10-6 | sc-364540 sc-364540A | 10 mg 50 mg | $383.00 $765.00 | ||
Moexipril is a potent angiotensin-converting enzyme (ACE) inhibitor that uniquely interacts with the active site of ACE, leading to a reduction in angiotensin II production. Its structure allows for specific hydrogen bonding and hydrophobic interactions, enhancing its binding affinity. The compound's kinetic profile reveals a competitive inhibition mechanism, which alters the enzymatic reaction rates. Furthermore, its lipophilic characteristics influence membrane permeability and distribution in biological environments. | ||||||
A-779 | 159432-28-7 (net) | sc-396002 | 1 mg | $154.00 | 4 | |
A-779 is a selective angiotensin receptor antagonist that exhibits unique binding dynamics with the angiotensin II receptor. Its structural conformation facilitates specific electrostatic interactions, promoting a high affinity for the receptor's active site. This compound demonstrates a distinct allosteric modulation effect, influencing downstream signaling pathways. Additionally, A-779's solubility properties enhance its distribution in various biological matrices, impacting its interaction kinetics and receptor engagement. | ||||||